Human Growth Hormone (GH)
Buy Human Growth Hormone (GH) - Click Here
Human Growth Hormone (GH) has been a subject of debate since I was a kid.Natural (endogenous) GH is produced by the pituitary gland. Children produce 2 i.u."spurts" 4-7 times per day for 4-5 non-consecutive days during a 2-3 week period (duringgrowth spurts). That would equal 32-70 i.u. in only a 4-5 day span. A healthy adult'spituitary releases only 0.5-1.5 i.u. daily.
GH has quickly become a very popular product for athletes looking to reach the top level Until the mid 1980's, the only available form of exogenous (occurring outside thebody) GH was manufactured by taking the pituitary glands of dead corpses (like there area lot of "live" corpses running around?) and grinding them up. (I am not joking!). TheGH was then extracted and purified through a series of expensive procedures, packed andsold by prescription only for use by children suffering from stunted growth. About 1987,this form of GH was linked to a fatal brain disease called CREUTZFELD-JAKOBDISEASE, and removed from the market.
Enter Genetech and synthetic GH. The first synthetic GH was produced bygenetically altering transformed mouse cells /Ecoli. Natural GH has a 191 amino acidsequence where as the Protropin brand of GH produced by Genetech contains 192 aminoacids in its sequence. This may have the affect of causing the body to produce GH antibodieswhich deactivate the GH. Most synthetics now contain the normal 191 amino acidsequence, of which there are over a dozen available today.
GH has 3 effects any athlete desires: GH helps the body burn more adipose (fat)tissue by promoting the release of fatty acids to be used as energy. Normally at rest, thebody uses about an equal division of fat and carbohydrate calories. When the endocrinesystem senses a low circulatory level of glucose, the hypothalamus-pituitary-axis (HPA)reacts by releasing GH. The GH then triggers (through a series of enzymic/chemicalreactions) the release of fatty acids from adipose stores so metabolic energy requirementscan be met. This means exogenous GH administration has been well documented to dothe same.
GH has a very potent anabolic (protein synthesis/tissue building) effect. Inexerting anabolic effects, it can cause both hyperplasia (an increase in the number ofmuscle cells) and muscular hypertrophy (the enlargement of muscle cells). This change incell number is permanent and therefore means more cells to make bigger. GH also has ananabolic effect on soft tissues such as tendons, cartilage, and other connective tissue. Thismeans old injuries repair and strength increases due to stronger connective tissue… bothat an accelerated rate. It is a well known fact that GH is a powerful anti-catabolic agent(protein sparing). This effect has allowed modern bodybuilders to retain or even addsignificant lean mass tissue during calorie restricted periods (cutting phases) and becomethe shredded monsters of the new era.
When using GH many athletes were less than satisfied with their results. Mostlikely this was because they bought bogus GH. It was common to find GH for a hard-corepro bodybuilder cost about $35,000 or more, yearly. To test GH, most simply bought apregnancy test kit, mix a vial of (hopefully) GH and place a drop or two in the test area.If the test result was “pregnant”..they had been screwed. Most pregnancy test kits test forelevated gonadoltropins (which HCG is and GH is not). For those few, whose bodiesmanufactured GH anti-bodies (and GH failed to work for you) sorry about your luck. GH,used properly, has overwhelmingly been renowned as a genetic equalizer if used for thatpurpose.
Any polled athlete chose to use GH as a performance enhancing drug should havefirst understand at least the basics of its actions.
GH itself is not responsible for the majority of the effects seen from GH use.Actually GH is only a precursor to the so-called "good stuff". When GH passes throughthe liver, it is converted into INSULIN-LIKE GROWTH FACTORS (such as IGF-1).IGF-1 is a very active but unstable chemical, which is why the body waits until the lastsecond to make it naturally. The liver has a limited capacity to convert excess GH intoIGF-1 unless other chemical hormone levels are also elevated. Insulin, T-4/T-3 thyroidhormones, gonadotropins, androgens/anabolic hormones, and even estrogen andcorticosteroids all play an important role in the positive effects of GH. So they too wereoften exogenously elevated in what was considered “the correct ratios” by the largest ofthe self administering athletes. For the liver to convert high levels of GH to IGF-1 severaltimes a day and cause a high quality anabolic response, it was commonly noted that T-3thyroid hormone and insulin also needed be increased to accomplish the desired effect.
Triacana may be strong enough to increase thyroid activity, but Cytomel was consideredto be a better choice. Though some seemed to disagree, most emphatically believed that afast-acting insulin such as HUMULIN-R or Humalog was a better and safer choice ofexogenous insulin since they allowed better timing and have a much shorter effectiveperiod. This allowed the athletes to time insulin activity with the active period of GH atthe optimum absorption times such as upon waking and the first few hours after a workout.The result was less chance of fat accumulation and a heightened anabolic response.Since GH suppresses natural T-3 thyroid hormone release, the exogenous administrationof Triacana or Cytomel allowed for an elevated calorie intake that was utilized more forbuilding muscle and soft tissue than for adipose tissue storage. Many pro bodybuildersused Clenbuterol and/or ephedrine stacks with GH while dieting. Since Clenbuterol and Ephedrine both suppress natural insulin release, they usually stacked the GH and Clenbuterol /Ephedrine with a synthetic T-3 thyroid hormone and sometimes with insulinas well. The use of insulin was dependent upon whether it was a bulking or dieting phaseand depending on how their body responded to exogenous insulin use.
*I can not stress enough how dangerous insulin use can be. Comas and death are quitepossible if used wrong. If you wish to use it, please see a doctor for monitoring.AAS and/or Clenbuterol further enhance the anabolic effects of GH. From all buta few polled it was reported that excellent muscle mass gains resulted with the use of GHwhen other chosen hormone levels were also met (*also see "cycles") and one couldafford it. Also, beware of fake GH. It is more common than you may realize. It is anillegal drug and the black market is not always honest.
The question of dosage was a big one. For the purpose of stunted growthmanufacturers of GH (due to pituitary hyophysially caused stunted growth) state 0.3 i.u.weekly per LB of body weight. So for a 235 LB bodybuilder that would equal 70.5 i.u.weekly, meaning a daily total of about 10-i.u. However, even 2-3i.u. daily did producesome nice results over a 6-8 week period when the other reported hormone requirementswere met as well. Short high dosage burst cycles too were noted to create these results(which will be discussed later) by the more elite of those polled.*GH is medically administered intramuscularly or subcutaneously (under the skin).*When multiple injections were utilized, I personally noted better results withsubcutaneous administration.
*1-mg=2.7 i.u. of GH and some products are listed as such.With exception of those few whose insert states otherwise, the dry unmixed GHsubstance maybe stored at room temperature. Once the solution has been mixed with thedry GH powder, (SWIRLED, DO NOT SHAKEN) the mixture must be refrigerated andlasts for 24-hours before it begins to degrade. An interesting product has becomeavailable called DEPO-NUTROPIN that has an active-life of about a month. This wouldallow for fewer injections and a reduced price. Also, several patents run out thisyear so many overseas and less expensive GH preparation will soon be available in theU.S. by prescription only.
*Though no negative side effects were reported, the available literature does listseveral serious ones: Kidneys and heart enlargement, high blood pressure, diabetes, thyroidhormone deficiency, and acromegaly. For the most part, they are rare to say the least andusually would be from extreme dosages and lengths of cycles. But like most hormones, youjust do not know until it is a fact for you. Kind of scary, huh?When GH was utilized with an insulin protocol, it was considered important tospace injection periods between GH and insulin about an hour. Also if GH was utilizedonly twice daily, it was reported best to avoid natural high points of GH release such asfirst thing in the a.m., post-work out, and right before bed. This was if GH was utilizedwithout insulin.
Reported Characteristics
Active-Life: Varies upon injection method Drug Class: Growth Hormone/IGF-1 Precursor (For injection) Average Reported Dosage: 2-16 i.u. total daily (1mg=2.7 i.u) Acne: None Water Retention: Very rare High Blood Pressure: Very rare Liver Toxic: None Aromatization: None High Anabolic/No Androgenic Effects
Trade Names
CORPORMON 4 I.U GENOTONORM 4 I.U. GENOTROPIN 2,3,4,12 I.U. GENOTROPIN 16 I.U. GRORM 2,4 I.U HUMATROPE 4 I.U. HUMATROPE 5MG HUMATROPE 16 I.U. NORDITROPIN 12 I.U. NUTROPIN 10 MG PROTROPIN 10 MG.. SAIZEN 10 I.U. SOMATOHORM 4 I.U. ZOMACTORS 4,12 I.U.
Tuesday, July 31, 2007
Thursday, July 26, 2007
Human Growth Hormone (GH)
Human Growth Hormone (GH)
Buy Human Growth Hormone (GH) - Click Here
Human Growth Hormone (GH) has been a subject of debate since I was a kid.Natural (endogenous) GH is produced by the pituitary gland. Children produce 2 i.u."spurts" 4-7 times per day for 4-5 non-consecutive days during a 2-3 week period (duringgrowth spurts). That would equal 32-70 i.u. in only a 4-5 day span. A healthy adult'spituitary releases only 0.5-1.5 i.u. daily.
GH has quickly become a very popular product for athletes looking to reach the top level Until the mid 1980's, the only available form of exogenous (occurring outside thebody) GH was manufactured by taking the pituitary glands of dead corpses (like there area lot of "live" corpses running around?) and grinding them up. (I am not joking!). TheGH was then extracted and purified through a series of expensive procedures, packed andsold by prescription only for use by children suffering from stunted growth. About 1987,this form of GH was linked to a fatal brain disease called CREUTZFELD-JAKOBDISEASE, and removed from the market.
Enter Genetech and synthetic GH. The first synthetic GH was produced bygenetically altering transformed mouse cells /Ecoli. Natural GH has a 191 amino acidsequence where as the Protropin brand of GH produced by Genetech contains 192 aminoacids in its sequence. This may have the affect of causing the body to produce GH antibodieswhich deactivate the GH. Most synthetics now contain the normal 191 amino acidsequence, of which there are over a dozen available today.
GH has 3 effects any athlete desires: GH helps the body burn more adipose (fat)tissue by promoting the release of fatty acids to be used as energy. Normally at rest, thebody uses about an equal division of fat and carbohydrate calories. When the endocrinesystem senses a low circulatory level of glucose, the hypothalamus-pituitary-axis (HPA)reacts by releasing GH. The GH then triggers (through a series of enzymic/chemicalreactions) the release of fatty acids from adipose stores so metabolic energy requirementscan be met. This means exogenous GH administration has been well documented to dothe same.
GH has a very potent anabolic (protein synthesis/tissue building) effect. Inexerting anabolic effects, it can cause both hyperplasia (an increase in the number ofmuscle cells) and muscular hypertrophy (the enlargement of muscle cells). This change incell number is permanent and therefore means more cells to make bigger. GH also has ananabolic effect on soft tissues such as tendons, cartilage, and other connective tissue. Thismeans old injuries repair and strength increases due to stronger connective tissue… bothat an accelerated rate. It is a well known fact that GH is a powerful anti-catabolic agent(protein sparing). This effect has allowed modern bodybuilders to retain or even addsignificant lean mass tissue during calorie restricted periods (cutting phases) and becomethe shredded monsters of the new era.
When using GH many athletes were less than satisfied with their results. Mostlikely this was because they bought bogus GH. It was common to find GH for a hard-corepro bodybuilder cost about $35,000 or more, yearly. To test GH, most simply bought apregnancy test kit, mix a vial of (hopefully) GH and place a drop or two in the test area.If the test result was “pregnant”..they had been screwed. Most pregnancy test kits test forelevated gonadoltropins (which HCG is and GH is not). For those few, whose bodiesmanufactured GH anti-bodies (and GH failed to work for you) sorry about your luck. GH,used properly, has overwhelmingly been renowned as a genetic equalizer if used for thatpurpose.
Any polled athlete chose to use GH as a performance enhancing drug should havefirst understand at least the basics of its actions.
GH itself is not responsible for the majority of the effects seen from GH use.Actually GH is only a precursor to the so-called "good stuff". When GH passes throughthe liver, it is converted into INSULIN-LIKE GROWTH FACTORS (such as IGF-1).IGF-1 is a very active but unstable chemical, which is why the body waits until the lastsecond to make it naturally. The liver has a limited capacity to convert excess GH intoIGF-1 unless other chemical hormone levels are also elevated. Insulin, T-4/T-3 thyroidhormones, gonadotropins, androgens/anabolic hormones, and even estrogen andcorticosteroids all play an important role in the positive effects of GH. So they too wereoften exogenously elevated in what was considered “the correct ratios” by the largest ofthe self administering athletes. For the liver to convert high levels of GH to IGF-1 severaltimes a day and cause a high quality anabolic response, it was commonly noted that T-3thyroid hormone and insulin also needed be increased to accomplish the desired effect.
Triacana may be strong enough to increase thyroid activity, but Cytomel was consideredto be a better choice. Though some seemed to disagree, most emphatically believed that afast-acting insulin such as HUMULIN-R or Humalog was a better and safer choice ofexogenous insulin since they allowed better timing and have a much shorter effectiveperiod. This allowed the athletes to time insulin activity with the active period of GH atthe optimum absorption times such as upon waking and the first few hours after a workout.The result was less chance of fat accumulation and a heightened anabolic response.Since GH suppresses natural T-3 thyroid hormone release, the exogenous administrationof Triacana or Cytomel allowed for an elevated calorie intake that was utilized more forbuilding muscle and soft tissue than for adipose tissue storage. Many pro bodybuildersused Clenbuterol and/or ephedrine stacks with GH while dieting. Since Clenbuterol and Ephedrine both suppress natural insulin release, they usually stacked the GH and Clenbuterol /Ephedrine with a synthetic T-3 thyroid hormone and sometimes with insulinas well. The use of insulin was dependent upon whether it was a bulking or dieting phaseand depending on how their body responded to exogenous insulin use.
*I can not stress enough how dangerous insulin use can be. Comas and death are quitepossible if used wrong. If you wish to use it, please see a doctor for monitoring.AAS and/or Clenbuterol further enhance the anabolic effects of GH. From all buta few polled it was reported that excellent muscle mass gains resulted with the use of GHwhen other chosen hormone levels were also met (*also see "cycles") and one couldafford it. Also, beware of fake GH. It is more common than you may realize. It is anillegal drug and the black market is not always honest.
The question of dosage was a big one. For the purpose of stunted growthmanufacturers of GH (due to pituitary hyophysially caused stunted growth) state 0.3 i.u.weekly per LB of body weight. So for a 235 LB bodybuilder that would equal 70.5 i.u.weekly, meaning a daily total of about 10-i.u. However, even 2-3i.u. daily did producesome nice results over a 6-8 week period when the other reported hormone requirementswere met as well. Short high dosage burst cycles too were noted to create these results(which will be discussed later) by the more elite of those polled.*GH is medically administered intramuscularly or subcutaneously (under the skin).*When multiple injections were utilized, I personally noted better results withsubcutaneous administration.
*1-mg=2.7 i.u. of GH and some products are listed as such.With exception of those few whose insert states otherwise, the dry unmixed GHsubstance maybe stored at room temperature. Once the solution has been mixed with thedry GH powder, (SWIRLED, DO NOT SHAKEN) the mixture must be refrigerated andlasts for 24-hours before it begins to degrade. An interesting product has becomeavailable called DEPO-NUTROPIN that has an active-life of about a month. This wouldallow for fewer injections and a reduced price. Also, several patents run out thisyear so many overseas and less expensive GH preparation will soon be available in theU.S. by prescription only.
*Though no negative side effects were reported, the available literature does listseveral serious ones: Kidneys and heart enlargement, high blood pressure, diabetes, thyroidhormone deficiency, and acromegaly. For the most part, they are rare to say the least andusually would be from extreme dosages and lengths of cycles. But like most hormones, youjust do not know until it is a fact for you. Kind of scary, huh?When GH was utilized with an insulin protocol, it was considered important tospace injection periods between GH and insulin about an hour. Also if GH was utilizedonly twice daily, it was reported best to avoid natural high points of GH release such asfirst thing in the a.m., post-work out, and right before bed. This was if GH was utilizedwithout insulin.
Reported Characteristics
Active-Life: Varies upon injection method Drug Class: Growth Hormone/IGF-1 Precursor (For injection) Average Reported Dosage: 2-16 i.u. total daily (1mg=2.7 i.u) Acne: None Water Retention: Very rare High Blood Pressure: Very rare Liver Toxic: None Aromatization: None High Anabolic/No Androgenic Effects
Trade Names
CORPORMON 4 I.U GENOTONORM 4 I.U. GENOTROPIN 2,3,4,12 I.U. GENOTROPIN 16 I.U. GRORM 2,4 I.U HUMATROPE 4 I.U. HUMATROPE 5MG HUMATROPE 16 I.U. NORDITROPIN 12 I.U. NUTROPIN 10 MG PROTROPIN 10 MG.. SAIZEN 10 I.U. SOMATOHORM 4 I.U. ZOMACTORS 4,12 I.U.
Buy Human Growth Hormone (GH) - Click Here
Human Growth Hormone (GH) has been a subject of debate since I was a kid.Natural (endogenous) GH is produced by the pituitary gland. Children produce 2 i.u."spurts" 4-7 times per day for 4-5 non-consecutive days during a 2-3 week period (duringgrowth spurts). That would equal 32-70 i.u. in only a 4-5 day span. A healthy adult'spituitary releases only 0.5-1.5 i.u. daily.
GH has quickly become a very popular product for athletes looking to reach the top level Until the mid 1980's, the only available form of exogenous (occurring outside thebody) GH was manufactured by taking the pituitary glands of dead corpses (like there area lot of "live" corpses running around?) and grinding them up. (I am not joking!). TheGH was then extracted and purified through a series of expensive procedures, packed andsold by prescription only for use by children suffering from stunted growth. About 1987,this form of GH was linked to a fatal brain disease called CREUTZFELD-JAKOBDISEASE, and removed from the market.
Enter Genetech and synthetic GH. The first synthetic GH was produced bygenetically altering transformed mouse cells /Ecoli. Natural GH has a 191 amino acidsequence where as the Protropin brand of GH produced by Genetech contains 192 aminoacids in its sequence. This may have the affect of causing the body to produce GH antibodieswhich deactivate the GH. Most synthetics now contain the normal 191 amino acidsequence, of which there are over a dozen available today.
GH has 3 effects any athlete desires: GH helps the body burn more adipose (fat)tissue by promoting the release of fatty acids to be used as energy. Normally at rest, thebody uses about an equal division of fat and carbohydrate calories. When the endocrinesystem senses a low circulatory level of glucose, the hypothalamus-pituitary-axis (HPA)reacts by releasing GH. The GH then triggers (through a series of enzymic/chemicalreactions) the release of fatty acids from adipose stores so metabolic energy requirementscan be met. This means exogenous GH administration has been well documented to dothe same.
GH has a very potent anabolic (protein synthesis/tissue building) effect. Inexerting anabolic effects, it can cause both hyperplasia (an increase in the number ofmuscle cells) and muscular hypertrophy (the enlargement of muscle cells). This change incell number is permanent and therefore means more cells to make bigger. GH also has ananabolic effect on soft tissues such as tendons, cartilage, and other connective tissue. Thismeans old injuries repair and strength increases due to stronger connective tissue… bothat an accelerated rate. It is a well known fact that GH is a powerful anti-catabolic agent(protein sparing). This effect has allowed modern bodybuilders to retain or even addsignificant lean mass tissue during calorie restricted periods (cutting phases) and becomethe shredded monsters of the new era.
When using GH many athletes were less than satisfied with their results. Mostlikely this was because they bought bogus GH. It was common to find GH for a hard-corepro bodybuilder cost about $35,000 or more, yearly. To test GH, most simply bought apregnancy test kit, mix a vial of (hopefully) GH and place a drop or two in the test area.If the test result was “pregnant”..they had been screwed. Most pregnancy test kits test forelevated gonadoltropins (which HCG is and GH is not). For those few, whose bodiesmanufactured GH anti-bodies (and GH failed to work for you) sorry about your luck. GH,used properly, has overwhelmingly been renowned as a genetic equalizer if used for thatpurpose.
Any polled athlete chose to use GH as a performance enhancing drug should havefirst understand at least the basics of its actions.
GH itself is not responsible for the majority of the effects seen from GH use.Actually GH is only a precursor to the so-called "good stuff". When GH passes throughthe liver, it is converted into INSULIN-LIKE GROWTH FACTORS (such as IGF-1).IGF-1 is a very active but unstable chemical, which is why the body waits until the lastsecond to make it naturally. The liver has a limited capacity to convert excess GH intoIGF-1 unless other chemical hormone levels are also elevated. Insulin, T-4/T-3 thyroidhormones, gonadotropins, androgens/anabolic hormones, and even estrogen andcorticosteroids all play an important role in the positive effects of GH. So they too wereoften exogenously elevated in what was considered “the correct ratios” by the largest ofthe self administering athletes. For the liver to convert high levels of GH to IGF-1 severaltimes a day and cause a high quality anabolic response, it was commonly noted that T-3thyroid hormone and insulin also needed be increased to accomplish the desired effect.
Triacana may be strong enough to increase thyroid activity, but Cytomel was consideredto be a better choice. Though some seemed to disagree, most emphatically believed that afast-acting insulin such as HUMULIN-R or Humalog was a better and safer choice ofexogenous insulin since they allowed better timing and have a much shorter effectiveperiod. This allowed the athletes to time insulin activity with the active period of GH atthe optimum absorption times such as upon waking and the first few hours after a workout.The result was less chance of fat accumulation and a heightened anabolic response.Since GH suppresses natural T-3 thyroid hormone release, the exogenous administrationof Triacana or Cytomel allowed for an elevated calorie intake that was utilized more forbuilding muscle and soft tissue than for adipose tissue storage. Many pro bodybuildersused Clenbuterol and/or ephedrine stacks with GH while dieting. Since Clenbuterol and Ephedrine both suppress natural insulin release, they usually stacked the GH and Clenbuterol /Ephedrine with a synthetic T-3 thyroid hormone and sometimes with insulinas well. The use of insulin was dependent upon whether it was a bulking or dieting phaseand depending on how their body responded to exogenous insulin use.
*I can not stress enough how dangerous insulin use can be. Comas and death are quitepossible if used wrong. If you wish to use it, please see a doctor for monitoring.AAS and/or Clenbuterol further enhance the anabolic effects of GH. From all buta few polled it was reported that excellent muscle mass gains resulted with the use of GHwhen other chosen hormone levels were also met (*also see "cycles") and one couldafford it. Also, beware of fake GH. It is more common than you may realize. It is anillegal drug and the black market is not always honest.
The question of dosage was a big one. For the purpose of stunted growthmanufacturers of GH (due to pituitary hyophysially caused stunted growth) state 0.3 i.u.weekly per LB of body weight. So for a 235 LB bodybuilder that would equal 70.5 i.u.weekly, meaning a daily total of about 10-i.u. However, even 2-3i.u. daily did producesome nice results over a 6-8 week period when the other reported hormone requirementswere met as well. Short high dosage burst cycles too were noted to create these results(which will be discussed later) by the more elite of those polled.*GH is medically administered intramuscularly or subcutaneously (under the skin).*When multiple injections were utilized, I personally noted better results withsubcutaneous administration.
*1-mg=2.7 i.u. of GH and some products are listed as such.With exception of those few whose insert states otherwise, the dry unmixed GHsubstance maybe stored at room temperature. Once the solution has been mixed with thedry GH powder, (SWIRLED, DO NOT SHAKEN) the mixture must be refrigerated andlasts for 24-hours before it begins to degrade. An interesting product has becomeavailable called DEPO-NUTROPIN that has an active-life of about a month. This wouldallow for fewer injections and a reduced price. Also, several patents run out thisyear so many overseas and less expensive GH preparation will soon be available in theU.S. by prescription only.
*Though no negative side effects were reported, the available literature does listseveral serious ones: Kidneys and heart enlargement, high blood pressure, diabetes, thyroidhormone deficiency, and acromegaly. For the most part, they are rare to say the least andusually would be from extreme dosages and lengths of cycles. But like most hormones, youjust do not know until it is a fact for you. Kind of scary, huh?When GH was utilized with an insulin protocol, it was considered important tospace injection periods between GH and insulin about an hour. Also if GH was utilizedonly twice daily, it was reported best to avoid natural high points of GH release such asfirst thing in the a.m., post-work out, and right before bed. This was if GH was utilizedwithout insulin.
Reported Characteristics
Active-Life: Varies upon injection method Drug Class: Growth Hormone/IGF-1 Precursor (For injection) Average Reported Dosage: 2-16 i.u. total daily (1mg=2.7 i.u) Acne: None Water Retention: Very rare High Blood Pressure: Very rare Liver Toxic: None Aromatization: None High Anabolic/No Androgenic Effects
Trade Names
CORPORMON 4 I.U GENOTONORM 4 I.U. GENOTROPIN 2,3,4,12 I.U. GENOTROPIN 16 I.U. GRORM 2,4 I.U HUMATROPE 4 I.U. HUMATROPE 5MG HUMATROPE 16 I.U. NORDITROPIN 12 I.U. NUTROPIN 10 MG PROTROPIN 10 MG.. SAIZEN 10 I.U. SOMATOHORM 4 I.U. ZOMACTORS 4,12 I.U.
Wednesday, July 25, 2007
Deca-Durabolin® (nandrolone decanoate)
Deca-Durabolin® (nandrolone decanoate)
Quick overview:
Active Life: 14-16 days
Drug Class: Anabolic/Androgenic Steroid (injectable)
Average Dose: Men 300-800 mg/week.....Women 50-100 mg/week
Acne: Yes, in higher dosages or sensitive individuals
Water Retention: Yes, but less than testosterone
High Blood Pressure: Dose depandant
Liver Toxic: No
Aromatization: Low, converts to less active norestrogens
DHT Conversion: No, converts to NOR-DHT with low activity
Decrease HPTA function: Yes, extreme
Other Info: Highly anabolic/moderate androgenic effects
Deca-Durabolin® is the Organon brand name for the injectable steroid nandrolone decanoate. This compound came around early in the wave of commercial steroid development, first being made available as a prescription medication in 1962.
World wide "Deca" is one of the most widely used anabolic steroids. Its popularity is due to the simple fact that it exhibits many very favorable properties. Structurally nandrolone is very similar to testosterone, although it lacks a carbon atom at the 19th position (hence its other name 19-nortestosterone). The resulting structure is a steroid that exhibits much weaker androgenic properties than testosterone. Of primary interest is the fact that nandrolone will not break down to a more potent metabolite in androgen target tissues. You may remember this is a significant problem with testosterone. Although nandrolone does undergo reduction via the same (5-alpha reductase) enzyme that produces DHT from testosterone, the result in this case is dihydronandrolone. This metabolite is weaker than the parent nandroloness, and is far less likely to cause unwanted androgenic side effects. Strong occurrences of oily skin, acne, body/facial hair growth and hair loss occur very rarely. It is however possible for androgenic activity to become apparent with this as any steroid, but with nandrolone higher than normal doses are usually responsible.
Nandrolone also show an extremely lower tendency for estrogen conversion. For comparison, the rate has been estimated to be only about 20% of that seen with testosterones. This is because while the liver can convert nandrolone to estradiol, in other more active sites of steroid aromatization such as adipose tissue nandrolone is far less open to this process'. Consequently estrogen related side effects are a much lower concern with this drug. An anti-estrogen is likewise rarely needed with Deca, gynecomastia only a worry among sensitive individuals. At the same time water retention is not a usual concern. This effect can occur however, but is most often related to higher dosages. The addition of Proviron and/or Nolvadex should prove sufficient enough to significantly reduce any occurrence. Clearly Deca is a very safe choice among steroids. Actually, many consider it to be the best overall steroid for a man to use when weighing the side effects and results. It should also be noted that in HIV studies, Deca has been shown not only to be effective at safely bringing up the lean body weight of patient, but also to be beneficial to the immune system.
It is of note however that nandrolone is believed to have some activity as a progestin in the body. Although progesterone is a c-19 steroid, removal of this group as in 19-norprogesterone creates a hormone with greater binding affinity for its corresponding receptor. Sharing this trait, many 19-nor anabolic steroids are shown to have some affinity for the progesterone receptor as well. This can lead to some progestin-like activity in the body, and may intensify related side effects. The side effects associated with progesterone are actually quite similar to those of estrogen, including negative feedback inhibition of testosterone production, enhanced rate of fat storage and possibly gynecomastia. Many believe the progestin activity of Deca notably contributes to suppression of testosterone synthesis, which can be marked despite a low tendency for estrogen conversion.
Deca is not known as a very "fast" builder. The muscle building effect of this drug is quite noticeable, but not dramatic. The slow onset and mild properties of this steroid therefore make it more suited for cycles with a longer duration. In general one can expect to gain muscle weight at about half the rate of that with an equal amount of testosterone. A cycle lasting eight to twelve weeks seems to make the most sense, expecting to elicit a slow, even gain of quality mass. Although active in the body for much longer, Deca is usually injected once or twice per week. The dosage for men is usually in the range of 300-600mg/week. If looking to be specific, it is believed that Deca will exhibit its optimal effect (best gain/side effect ratio) at around 2mg per pound of lean bodyweight/weekly. Deca is also a popular steroid among female bodybuilders. They take a much lower dosage on average than men of course, usually around 50mg weekly. Although only slightly androgenic, women are occasionally confronted with virilization symptoms when taking this compound. Should this become a concern, the shorter acting nandrolone Durabolin would be a safer option. This drug stays active for only a few days, greatly reducing the impact of androgenic buildup if withdrawal were indicated.
Endogenous testosterone levels can be a concern with Deca-Durabolin, especially after long cycles. It is therefore mandatory to incorporate ancillary drugs at the conclusion of therapy. An estrogen antagonist such as Clomid or Nolvadex is therefore commonly used for a few weeks. These both provide a good level of testosterone stimulation, although they may take a couple of weeks to show the best effect. HCG injections could be added for extra reassurance, acting to rapidly restore the normal ability of the testes to respond to the resumed release of gonadotropins. For this purpose one could administer three injections of 2500-50001.U., spaced five days apart. After which point the antagonist is continued alone for a few more weeks in an effort to stabilize the production of testosterone. Remember not to begin post cycle therapy (PCT) until after Deca has been withdrawn for around three weeks. Deca stays active for quite some time so the ancillary drugs will not be able to exhibit their optimal effect when the steroid is still being released into the bloodstream. The major drawback for competitive purposes is that in many cases nandrolone metabolites will be detectable in a drug screen for up to a year (or more) after use. This is clearly due to the form of administration. Esterified compounds have a high affinity to stay stored in fatty tissues. While we can accurately estimate the time frame it will take for a given dose to enter circulation from an injection site, we cannot know for sure that 100% of the steroid will have been metabolized at any given point. Small amounts may indeed be stubborn in leaving fatty tissue, particularly after heavy, longer-term use. Some quantity of nandrolone decanoate may therefore be left to sporadically enter into the blood stream many months after use. This process may be further aggravated when dieting for a show, a time when body fat stores are being actively depleted (possibly freeing more steroid). This has no doubt been the cause for many unexpected positives on a drug screen. The fact that nandrolone has been isolated as the "hands-off" injectable for the drug tested athlete is most likely due to its popularity (and therefore common appearance on drug screens). The same risk would of course hold true for other long chain esterified injectables such as Equipoise, and Primobolan.
Those not worried about drug screens are likely to find the low water retention and good effect of this drug favorable for use in pre-contest cutting stacks. A combination of Deca and Winstrol during the weeks/months leading up to a show for example, is noted to greatly enhance to look of muscularity and definition. A strong non-aromatizing androgen like Halotestin or trenbolone could be further added, providing an enhanced level of hardness and density to the muscles. Being an acceptable anabolic, Deca can also be incorporated into bulk cycles with good results. The classic Deca and Dianabol cycle has been a basic for decades, and always seems to provide excellent muscle growth. A stronger androgen such as Anadrol or testosterone could also be substituted, producing greater results. When mixed with Deca, the androgen dosage can be kept lower than if used alone, hopefully making the cycle more comfortable. Additionally one may choose to continue Deca for a number of few weeks after the androgen has been stopped. This will hopefully harden up some of the bloat produced by the androgen, giving a more quality appearance. Remember that endogenous testosterone production will not resume during Deca therapy, and ancillaries are likewise still needed.
Quick overview:
Active Life: 14-16 days
Drug Class: Anabolic/Androgenic Steroid (injectable)
Average Dose: Men 300-800 mg/week.....Women 50-100 mg/week
Acne: Yes, in higher dosages or sensitive individuals
Water Retention: Yes, but less than testosterone
High Blood Pressure: Dose depandant
Liver Toxic: No
Aromatization: Low, converts to less active norestrogens
DHT Conversion: No, converts to NOR-DHT with low activity
Decrease HPTA function: Yes, extreme
Other Info: Highly anabolic/moderate androgenic effects
Deca-Durabolin® is the Organon brand name for the injectable steroid nandrolone decanoate. This compound came around early in the wave of commercial steroid development, first being made available as a prescription medication in 1962.
World wide "Deca" is one of the most widely used anabolic steroids. Its popularity is due to the simple fact that it exhibits many very favorable properties. Structurally nandrolone is very similar to testosterone, although it lacks a carbon atom at the 19th position (hence its other name 19-nortestosterone). The resulting structure is a steroid that exhibits much weaker androgenic properties than testosterone. Of primary interest is the fact that nandrolone will not break down to a more potent metabolite in androgen target tissues. You may remember this is a significant problem with testosterone. Although nandrolone does undergo reduction via the same (5-alpha reductase) enzyme that produces DHT from testosterone, the result in this case is dihydronandrolone. This metabolite is weaker than the parent nandroloness, and is far less likely to cause unwanted androgenic side effects. Strong occurrences of oily skin, acne, body/facial hair growth and hair loss occur very rarely. It is however possible for androgenic activity to become apparent with this as any steroid, but with nandrolone higher than normal doses are usually responsible.
Nandrolone also show an extremely lower tendency for estrogen conversion. For comparison, the rate has been estimated to be only about 20% of that seen with testosterones. This is because while the liver can convert nandrolone to estradiol, in other more active sites of steroid aromatization such as adipose tissue nandrolone is far less open to this process'. Consequently estrogen related side effects are a much lower concern with this drug. An anti-estrogen is likewise rarely needed with Deca, gynecomastia only a worry among sensitive individuals. At the same time water retention is not a usual concern. This effect can occur however, but is most often related to higher dosages. The addition of Proviron and/or Nolvadex should prove sufficient enough to significantly reduce any occurrence. Clearly Deca is a very safe choice among steroids. Actually, many consider it to be the best overall steroid for a man to use when weighing the side effects and results. It should also be noted that in HIV studies, Deca has been shown not only to be effective at safely bringing up the lean body weight of patient, but also to be beneficial to the immune system.
It is of note however that nandrolone is believed to have some activity as a progestin in the body. Although progesterone is a c-19 steroid, removal of this group as in 19-norprogesterone creates a hormone with greater binding affinity for its corresponding receptor. Sharing this trait, many 19-nor anabolic steroids are shown to have some affinity for the progesterone receptor as well. This can lead to some progestin-like activity in the body, and may intensify related side effects. The side effects associated with progesterone are actually quite similar to those of estrogen, including negative feedback inhibition of testosterone production, enhanced rate of fat storage and possibly gynecomastia. Many believe the progestin activity of Deca notably contributes to suppression of testosterone synthesis, which can be marked despite a low tendency for estrogen conversion.
Deca is not known as a very "fast" builder. The muscle building effect of this drug is quite noticeable, but not dramatic. The slow onset and mild properties of this steroid therefore make it more suited for cycles with a longer duration. In general one can expect to gain muscle weight at about half the rate of that with an equal amount of testosterone. A cycle lasting eight to twelve weeks seems to make the most sense, expecting to elicit a slow, even gain of quality mass. Although active in the body for much longer, Deca is usually injected once or twice per week. The dosage for men is usually in the range of 300-600mg/week. If looking to be specific, it is believed that Deca will exhibit its optimal effect (best gain/side effect ratio) at around 2mg per pound of lean bodyweight/weekly. Deca is also a popular steroid among female bodybuilders. They take a much lower dosage on average than men of course, usually around 50mg weekly. Although only slightly androgenic, women are occasionally confronted with virilization symptoms when taking this compound. Should this become a concern, the shorter acting nandrolone Durabolin would be a safer option. This drug stays active for only a few days, greatly reducing the impact of androgenic buildup if withdrawal were indicated.
Endogenous testosterone levels can be a concern with Deca-Durabolin, especially after long cycles. It is therefore mandatory to incorporate ancillary drugs at the conclusion of therapy. An estrogen antagonist such as Clomid or Nolvadex is therefore commonly used for a few weeks. These both provide a good level of testosterone stimulation, although they may take a couple of weeks to show the best effect. HCG injections could be added for extra reassurance, acting to rapidly restore the normal ability of the testes to respond to the resumed release of gonadotropins. For this purpose one could administer three injections of 2500-50001.U., spaced five days apart. After which point the antagonist is continued alone for a few more weeks in an effort to stabilize the production of testosterone. Remember not to begin post cycle therapy (PCT) until after Deca has been withdrawn for around three weeks. Deca stays active for quite some time so the ancillary drugs will not be able to exhibit their optimal effect when the steroid is still being released into the bloodstream. The major drawback for competitive purposes is that in many cases nandrolone metabolites will be detectable in a drug screen for up to a year (or more) after use. This is clearly due to the form of administration. Esterified compounds have a high affinity to stay stored in fatty tissues. While we can accurately estimate the time frame it will take for a given dose to enter circulation from an injection site, we cannot know for sure that 100% of the steroid will have been metabolized at any given point. Small amounts may indeed be stubborn in leaving fatty tissue, particularly after heavy, longer-term use. Some quantity of nandrolone decanoate may therefore be left to sporadically enter into the blood stream many months after use. This process may be further aggravated when dieting for a show, a time when body fat stores are being actively depleted (possibly freeing more steroid). This has no doubt been the cause for many unexpected positives on a drug screen. The fact that nandrolone has been isolated as the "hands-off" injectable for the drug tested athlete is most likely due to its popularity (and therefore common appearance on drug screens). The same risk would of course hold true for other long chain esterified injectables such as Equipoise, and Primobolan.
Those not worried about drug screens are likely to find the low water retention and good effect of this drug favorable for use in pre-contest cutting stacks. A combination of Deca and Winstrol during the weeks/months leading up to a show for example, is noted to greatly enhance to look of muscularity and definition. A strong non-aromatizing androgen like Halotestin or trenbolone could be further added, providing an enhanced level of hardness and density to the muscles. Being an acceptable anabolic, Deca can also be incorporated into bulk cycles with good results. The classic Deca and Dianabol cycle has been a basic for decades, and always seems to provide excellent muscle growth. A stronger androgen such as Anadrol or testosterone could also be substituted, producing greater results. When mixed with Deca, the androgen dosage can be kept lower than if used alone, hopefully making the cycle more comfortable. Additionally one may choose to continue Deca for a number of few weeks after the androgen has been stopped. This will hopefully harden up some of the bloat produced by the androgen, giving a more quality appearance. Remember that endogenous testosterone production will not resume during Deca therapy, and ancillaries are likewise still needed.
Sunday, July 22, 2007
Equipoise (boldenone undecylenate)
Equipoise (boldenone undecylenate)
Quick overview:
Active Life: 14-16 days
Drug Class: Anabolic/Androgenic Steroid (for injection)
Average Dose: Men 400-600 mg/week......Women 50-150 mg/week
Acne: Rare
Water Retention: Low
High Blood Pressure: Rare
Liver Toxic: No
Aromatization: Some, about 50% less than testosterone
DHT Conversion: Low
Decrease HPTA function: Moderate
Equipoise® is the popular brand name for the veterinary injectable steroid boldenone undecylenate. It is a derivative of testosterone, which exhibits strong anabolic and moderately androgenic properties. The undecylenate ester greatly extends the activity of the drug (the undecylenate ester is only one carbon atom longer than decanoate), so that clinically injections would need to be repeated every three or four weeks. In the veterinary feild Equipoise is most commonly used on horses, exhibiting a pronounced effect on lean bodyweight, appetite and general disposition of the animal. As with all steroids, this compound shows a marked ability for increasing red blood cell production. In recent years this compound has become a favorite among athletes. Many consider it an ideal replacement to Deca-Durabolin.
The side effects of Equipoise are generally mild. The structure of boldenone does allow it to convert into estrogen, but it does not have an extremely high affinity to do so. If we look at aromatization studies, they suggest that its rate of estrogen conversion should be about half that of testosterone's. Water retention with this drug would therefore be slightly higher than that with Deca-Durabolin (with an estimated 20% conversion), but much less than we would find with a stronger compound as Testosterone. While there is still a chance of encountering an estrogen related side effect as such when using Equipoise, problems are usually not encountered at a moderate dosage level. Gynecomastia might become a problem, but usually only with very sensitive individuals or (again) with those using higher dosages. If estrogenic effects become a problem, the addition of Nolvadex should of course make the cycle more tolerable. An anti-aromatase such as Arimidex, Femara, or Amonasin would be a stronger option, however probably not necessary with such a mild drug.
Although typically dosage related, Equipoise can also produce distinct androgenic side effects. Oily skin, acne, increased aggression and hair loss are all possible with this compound. Women find this drug quite comfortable, virilization symptoms usually unheard of when taken at low doses. Boldenone does reduce to a more potent androgen (dihydroboldenone) via the 5alpha reductase enzyme (which produces DHT from testosterone), however its affinity for this interaction in the human body is low to nonexistent. Therefore the reductase inhibitor Proscar would not be of much use with Equipoise, as it would be blocking what is at best an insignificant path of metabolism for the steroid. Although this drug is relatively mild, it still has a depressive effect on endogenous testosterone levels, therefore a proper post cycle therapy HCG and Clomid/Nolvadex is needed at the conclusion of each cycle to avoid a "crash". A waiting time of around 3 weeks is required before starting PCT, enabling enough of the drug to clear one's system to make PCT effective.
In order to maintain stable blood levels, Equipoise should be injected at least once per week. It is most commonly used at a dosage of 400-600mg per week for men, 50-150 mg per week for women.
Equipoise is not a rapid mass builder, but will provide a slow but steady gain of strength and quality muscle mass. The most positive effects of this drug are seen when it is used for longer cycles, usually lasting at least 10 weeks in length. The muscle gained should not be the smooth bulk seen with androgens, but instead a very defined and solid look. Since water bloat is not contributing greatly to the diameter of the muscle, much of the size gained on a cycle of Equipoise can be retained after the drug has been discontinued. It is interesting to note that structurally Equipoise and the classic bulking drug Dianabol are almost identical. In the case of Equipoise the compound uses a l7beta ester (undecylenate), while Dianabol is 17 alpha alkylated. Aside from that difference, the drugs are basically the same. Of course they act quite differently in the body, which goes to show the 17-methylation effects more than just the oral efficancy of a steroid.
As discussed earlier, Equipoise is a very versatile compound. We can create a number of drug combinations with it depending on the desired result. For mass, one may want to stack it with Anadrol or an injectable testosterone. The result should be an incredible gain of muscle size and strength, without the same intensity of side effects if using the androgen (at a higher dose) alone. When used in a cutting cycle, muscle hardness and density can be greatly improved when combining Equipoise with a non-aromatizable steroid such as trenbolone acetate, Halotestin, or Winstrol. For some however, even the low buildup of estrogen associated with this compound is enough to relegate its use to bulking cycles only.
Equipoise is not an ideal steroid for the drug tested athlete however. This drug has the tendency to produce detectable metabolites in the urine months after use, a worry most commonly associated with Deca-Durabolin. This is of course due to the high oil solubility of long chain esterified injectable steroids, a property which enables the drug to remain deposited in fatty tissues for extended periods of time. While this will reliably slow the release of steroid into the blood stream, it also allows small residual amounts to remain present in the body far after the initial injection. The release of stubborn stores of hormone would no doubt also be enhanced around contest time, a period when the athlete drastically attempts to mobilize unwanted body fat. If enough were used in the off-season, the athlete may actually fail a drug screen for boldenone although many months may have past since the drug was last injected.
Quick overview:
Active Life: 14-16 days
Drug Class: Anabolic/Androgenic Steroid (for injection)
Average Dose: Men 400-600 mg/week......Women 50-150 mg/week
Acne: Rare
Water Retention: Low
High Blood Pressure: Rare
Liver Toxic: No
Aromatization: Some, about 50% less than testosterone
DHT Conversion: Low
Decrease HPTA function: Moderate
Equipoise® is the popular brand name for the veterinary injectable steroid boldenone undecylenate. It is a derivative of testosterone, which exhibits strong anabolic and moderately androgenic properties. The undecylenate ester greatly extends the activity of the drug (the undecylenate ester is only one carbon atom longer than decanoate), so that clinically injections would need to be repeated every three or four weeks. In the veterinary feild Equipoise is most commonly used on horses, exhibiting a pronounced effect on lean bodyweight, appetite and general disposition of the animal. As with all steroids, this compound shows a marked ability for increasing red blood cell production. In recent years this compound has become a favorite among athletes. Many consider it an ideal replacement to Deca-Durabolin.
The side effects of Equipoise are generally mild. The structure of boldenone does allow it to convert into estrogen, but it does not have an extremely high affinity to do so. If we look at aromatization studies, they suggest that its rate of estrogen conversion should be about half that of testosterone's. Water retention with this drug would therefore be slightly higher than that with Deca-Durabolin (with an estimated 20% conversion), but much less than we would find with a stronger compound as Testosterone. While there is still a chance of encountering an estrogen related side effect as such when using Equipoise, problems are usually not encountered at a moderate dosage level. Gynecomastia might become a problem, but usually only with very sensitive individuals or (again) with those using higher dosages. If estrogenic effects become a problem, the addition of Nolvadex should of course make the cycle more tolerable. An anti-aromatase such as Arimidex, Femara, or Amonasin would be a stronger option, however probably not necessary with such a mild drug.
Although typically dosage related, Equipoise can also produce distinct androgenic side effects. Oily skin, acne, increased aggression and hair loss are all possible with this compound. Women find this drug quite comfortable, virilization symptoms usually unheard of when taken at low doses. Boldenone does reduce to a more potent androgen (dihydroboldenone) via the 5alpha reductase enzyme (which produces DHT from testosterone), however its affinity for this interaction in the human body is low to nonexistent. Therefore the reductase inhibitor Proscar would not be of much use with Equipoise, as it would be blocking what is at best an insignificant path of metabolism for the steroid. Although this drug is relatively mild, it still has a depressive effect on endogenous testosterone levels, therefore a proper post cycle therapy HCG and Clomid/Nolvadex is needed at the conclusion of each cycle to avoid a "crash". A waiting time of around 3 weeks is required before starting PCT, enabling enough of the drug to clear one's system to make PCT effective.
In order to maintain stable blood levels, Equipoise should be injected at least once per week. It is most commonly used at a dosage of 400-600mg per week for men, 50-150 mg per week for women.
Equipoise is not a rapid mass builder, but will provide a slow but steady gain of strength and quality muscle mass. The most positive effects of this drug are seen when it is used for longer cycles, usually lasting at least 10 weeks in length. The muscle gained should not be the smooth bulk seen with androgens, but instead a very defined and solid look. Since water bloat is not contributing greatly to the diameter of the muscle, much of the size gained on a cycle of Equipoise can be retained after the drug has been discontinued. It is interesting to note that structurally Equipoise and the classic bulking drug Dianabol are almost identical. In the case of Equipoise the compound uses a l7beta ester (undecylenate), while Dianabol is 17 alpha alkylated. Aside from that difference, the drugs are basically the same. Of course they act quite differently in the body, which goes to show the 17-methylation effects more than just the oral efficancy of a steroid.
As discussed earlier, Equipoise is a very versatile compound. We can create a number of drug combinations with it depending on the desired result. For mass, one may want to stack it with Anadrol or an injectable testosterone. The result should be an incredible gain of muscle size and strength, without the same intensity of side effects if using the androgen (at a higher dose) alone. When used in a cutting cycle, muscle hardness and density can be greatly improved when combining Equipoise with a non-aromatizable steroid such as trenbolone acetate, Halotestin, or Winstrol. For some however, even the low buildup of estrogen associated with this compound is enough to relegate its use to bulking cycles only.
Equipoise is not an ideal steroid for the drug tested athlete however. This drug has the tendency to produce detectable metabolites in the urine months after use, a worry most commonly associated with Deca-Durabolin. This is of course due to the high oil solubility of long chain esterified injectable steroids, a property which enables the drug to remain deposited in fatty tissues for extended periods of time. While this will reliably slow the release of steroid into the blood stream, it also allows small residual amounts to remain present in the body far after the initial injection. The release of stubborn stores of hormone would no doubt also be enhanced around contest time, a period when the athlete drastically attempts to mobilize unwanted body fat. If enough were used in the off-season, the athlete may actually fail a drug screen for boldenone although many months may have past since the drug was last injected.
Saturday, July 21, 2007
Deca-Durabolin® (nandrolone decanoate)
Deca-Durabolin® (nandrolone decanoate)
Quick overview:
Active Life: 14-16 days
Drug Class: Anabolic/Androgenic Steroid (injectable)
Average Dose: Men 300-800 mg/week.....Women 50-100 mg/week
Acne: Yes, in higher dosages or sensitive individuals
Water Retention: Yes, but less than testosterone
High Blood Pressure: Dose depandant
Liver Toxic: No
Aromatization: Low, converts to less active norestrogens
DHT Conversion: No, converts to NOR-DHT with low activity
Decrease HPTA function: Yes, extreme
Other Info: Highly anabolic/moderate androgenic effects
Deca-Durabolin® is the Organon brand name for the injectable steroid nandrolone decanoate. This compound came around early in the wave of commercial steroid development, first being made available as a prescription medication in 1962.
World wide "Deca" is one of the most widely used anabolic steroids. Its popularity is due to the simple fact that it exhibits many very favorable properties. Structurally nandrolone is very similar to testosterone, although it lacks a carbon atom at the 19th position (hence its other name 19-nortestosterone). The resulting structure is a steroid that exhibits much weaker androgenic properties than testosterone. Of primary interest is the fact that nandrolone will not break down to a more potent metabolite in androgen target tissues. You may remember this is a significant problem with testosterone. Although nandrolone does undergo reduction via the same (5-alpha reductase) enzyme that produces DHT from testosterone, the result in this case is dihydronandrolone. This metabolite is weaker than the parent nandroloness, and is far less likely to cause unwanted androgenic side effects. Strong occurrences of oily skin, acne, body/facial hair growth and hair loss occur very rarely. It is however possible for androgenic activity to become apparent with this as any steroid, but with nandrolone higher than normal doses are usually responsible.
Nandrolone also show an extremely lower tendency for estrogen conversion. For comparison, the rate has been estimated to be only about 20% of that seen with testosterones. This is because while the liver can convert nandrolone to estradiol, in other more active sites of steroid aromatization such as adipose tissue nandrolone is far less open to this process'. Consequently estrogen related side effects are a much lower concern with this drug. An anti-estrogen is likewise rarely needed with Deca, gynecomastia only a worry among sensitive individuals. At the same time water retention is not a usual concern. This effect can occur however, but is most often related to higher dosages. The addition of Proviron and/or Nolvadex should prove sufficient enough to significantly reduce any occurrence. Clearly Deca is a very safe choice among steroids. Actually, many consider it to be the best overall steroid for a man to use when weighing the side effects and results. It should also be noted that in HIV studies, Deca has been shown not only to be effective at safely bringing up the lean body weight of patient, but also to be beneficial to the immune system.
It is of note however that nandrolone is believed to have some activity as a progestin in the body. Although progesterone is a c-19 steroid, removal of this group as in 19-norprogesterone creates a hormone with greater binding affinity for its corresponding receptor. Sharing this trait, many 19-nor anabolic steroids are shown to have some affinity for the progesterone receptor as well. This can lead to some progestin-like activity in the body, and may intensify related side effects. The side effects associated with progesterone are actually quite similar to those of estrogen, including negative feedback inhibition of testosterone production, enhanced rate of fat storage and possibly gynecomastia. Many believe the progestin activity of Deca notably contributes to suppression of testosterone synthesis, which can be marked despite a low tendency for estrogen conversion.
Deca is not known as a very "fast" builder. The muscle building effect of this drug is quite noticeable, but not dramatic. The slow onset and mild properties of this steroid therefore make it more suited for cycles with a longer duration. In general one can expect to gain muscle weight at about half the rate of that with an equal amount of testosterone. A cycle lasting eight to twelve weeks seems to make the most sense, expecting to elicit a slow, even gain of quality mass. Although active in the body for much longer, Deca is usually injected once or twice per week. The dosage for men is usually in the range of 300-600mg/week. If looking to be specific, it is believed that Deca will exhibit its optimal effect (best gain/side effect ratio) at around 2mg per pound of lean bodyweight/weekly. Deca is also a popular steroid among female bodybuilders. They take a much lower dosage on average than men of course, usually around 50mg weekly. Although only slightly androgenic, women are occasionally confronted with virilization symptoms when taking this compound. Should this become a concern, the shorter acting nandrolone Durabolin would be a safer option. This drug stays active for only a few days, greatly reducing the impact of androgenic buildup if withdrawal were indicated.
Endogenous testosterone levels can be a concern with Deca-Durabolin, especially after long cycles. It is therefore mandatory to incorporate ancillary drugs at the conclusion of therapy. An estrogen antagonist such as Clomid or Nolvadex is therefore commonly used for a few weeks. These both provide a good level of testosterone stimulation, although they may take a couple of weeks to show the best effect. HCG injections could be added for extra reassurance, acting to rapidly restore the normal ability of the testes to respond to the resumed release of gonadotropins. For this purpose one could administer three injections of 2500-50001.U., spaced five days apart. After which point the antagonist is continued alone for a few more weeks in an effort to stabilize the production of testosterone. Remember not to begin post cycle therapy (PCT) until after Deca has been withdrawn for around three weeks. Deca stays active for quite some time so the ancillary drugs will not be able to exhibit their optimal effect when the steroid is still being released into the bloodstream. The major drawback for competitive purposes is that in many cases nandrolone metabolites will be detectable in a drug screen for up to a year (or more) after use. This is clearly due to the form of administration. Esterified compounds have a high affinity to stay stored in fatty tissues. While we can accurately estimate the time frame it will take for a given dose to enter circulation from an injection site, we cannot know for sure that 100% of the steroid will have been metabolized at any given point. Small amounts may indeed be stubborn in leaving fatty tissue, particularly after heavy, longer-term use. Some quantity of nandrolone decanoate may therefore be left to sporadically enter into the blood stream many months after use. This process may be further aggravated when dieting for a show, a time when body fat stores are being actively depleted (possibly freeing more steroid). This has no doubt been the cause for many unexpected positives on a drug screen. The fact that nandrolone has been isolated as the "hands-off" injectable for the drug tested athlete is most likely due to its popularity (and therefore common appearance on drug screens). The same risk would of course hold true for other long chain esterified injectables such as Equipoise, and Primobolan.
Those not worried about drug screens are likely to find the low water retention and good effect of this drug favorable for use in pre-contest cutting stacks. A combination of Deca and Winstrol during the weeks/months leading up to a show for example, is noted to greatly enhance to look of muscularity and definition. A strong non-aromatizing androgen like Halotestin or trenbolone could be further added, providing an enhanced level of hardness and density to the muscles. Being an acceptable anabolic, Deca can also be incorporated into bulk cycles with good results. The classic Deca and Dianabol cycle has been a basic for decades, and always seems to provide excellent muscle growth. A stronger androgen such as Anadrol or testosterone could also be substituted, producing greater results. When mixed with Deca, the androgen dosage can be kept lower than if used alone, hopefully making the cycle more comfortable. Additionally one may choose to continue Deca for a number of few weeks after the androgen has been stopped. This will hopefully harden up some of the bloat produced by the androgen, giving a more quality appearance. Remember that endogenous testosterone production will not resume during Deca therapy, and ancillaries are likewise still needed.
Quick overview:
Active Life: 14-16 days
Drug Class: Anabolic/Androgenic Steroid (injectable)
Average Dose: Men 300-800 mg/week.....Women 50-100 mg/week
Acne: Yes, in higher dosages or sensitive individuals
Water Retention: Yes, but less than testosterone
High Blood Pressure: Dose depandant
Liver Toxic: No
Aromatization: Low, converts to less active norestrogens
DHT Conversion: No, converts to NOR-DHT with low activity
Decrease HPTA function: Yes, extreme
Other Info: Highly anabolic/moderate androgenic effects
Deca-Durabolin® is the Organon brand name for the injectable steroid nandrolone decanoate. This compound came around early in the wave of commercial steroid development, first being made available as a prescription medication in 1962.
World wide "Deca" is one of the most widely used anabolic steroids. Its popularity is due to the simple fact that it exhibits many very favorable properties. Structurally nandrolone is very similar to testosterone, although it lacks a carbon atom at the 19th position (hence its other name 19-nortestosterone). The resulting structure is a steroid that exhibits much weaker androgenic properties than testosterone. Of primary interest is the fact that nandrolone will not break down to a more potent metabolite in androgen target tissues. You may remember this is a significant problem with testosterone. Although nandrolone does undergo reduction via the same (5-alpha reductase) enzyme that produces DHT from testosterone, the result in this case is dihydronandrolone. This metabolite is weaker than the parent nandroloness, and is far less likely to cause unwanted androgenic side effects. Strong occurrences of oily skin, acne, body/facial hair growth and hair loss occur very rarely. It is however possible for androgenic activity to become apparent with this as any steroid, but with nandrolone higher than normal doses are usually responsible.
Nandrolone also show an extremely lower tendency for estrogen conversion. For comparison, the rate has been estimated to be only about 20% of that seen with testosterones. This is because while the liver can convert nandrolone to estradiol, in other more active sites of steroid aromatization such as adipose tissue nandrolone is far less open to this process'. Consequently estrogen related side effects are a much lower concern with this drug. An anti-estrogen is likewise rarely needed with Deca, gynecomastia only a worry among sensitive individuals. At the same time water retention is not a usual concern. This effect can occur however, but is most often related to higher dosages. The addition of Proviron and/or Nolvadex should prove sufficient enough to significantly reduce any occurrence. Clearly Deca is a very safe choice among steroids. Actually, many consider it to be the best overall steroid for a man to use when weighing the side effects and results. It should also be noted that in HIV studies, Deca has been shown not only to be effective at safely bringing up the lean body weight of patient, but also to be beneficial to the immune system.
It is of note however that nandrolone is believed to have some activity as a progestin in the body. Although progesterone is a c-19 steroid, removal of this group as in 19-norprogesterone creates a hormone with greater binding affinity for its corresponding receptor. Sharing this trait, many 19-nor anabolic steroids are shown to have some affinity for the progesterone receptor as well. This can lead to some progestin-like activity in the body, and may intensify related side effects. The side effects associated with progesterone are actually quite similar to those of estrogen, including negative feedback inhibition of testosterone production, enhanced rate of fat storage and possibly gynecomastia. Many believe the progestin activity of Deca notably contributes to suppression of testosterone synthesis, which can be marked despite a low tendency for estrogen conversion.
Deca is not known as a very "fast" builder. The muscle building effect of this drug is quite noticeable, but not dramatic. The slow onset and mild properties of this steroid therefore make it more suited for cycles with a longer duration. In general one can expect to gain muscle weight at about half the rate of that with an equal amount of testosterone. A cycle lasting eight to twelve weeks seems to make the most sense, expecting to elicit a slow, even gain of quality mass. Although active in the body for much longer, Deca is usually injected once or twice per week. The dosage for men is usually in the range of 300-600mg/week. If looking to be specific, it is believed that Deca will exhibit its optimal effect (best gain/side effect ratio) at around 2mg per pound of lean bodyweight/weekly. Deca is also a popular steroid among female bodybuilders. They take a much lower dosage on average than men of course, usually around 50mg weekly. Although only slightly androgenic, women are occasionally confronted with virilization symptoms when taking this compound. Should this become a concern, the shorter acting nandrolone Durabolin would be a safer option. This drug stays active for only a few days, greatly reducing the impact of androgenic buildup if withdrawal were indicated.
Endogenous testosterone levels can be a concern with Deca-Durabolin, especially after long cycles. It is therefore mandatory to incorporate ancillary drugs at the conclusion of therapy. An estrogen antagonist such as Clomid or Nolvadex is therefore commonly used for a few weeks. These both provide a good level of testosterone stimulation, although they may take a couple of weeks to show the best effect. HCG injections could be added for extra reassurance, acting to rapidly restore the normal ability of the testes to respond to the resumed release of gonadotropins. For this purpose one could administer three injections of 2500-50001.U., spaced five days apart. After which point the antagonist is continued alone for a few more weeks in an effort to stabilize the production of testosterone. Remember not to begin post cycle therapy (PCT) until after Deca has been withdrawn for around three weeks. Deca stays active for quite some time so the ancillary drugs will not be able to exhibit their optimal effect when the steroid is still being released into the bloodstream. The major drawback for competitive purposes is that in many cases nandrolone metabolites will be detectable in a drug screen for up to a year (or more) after use. This is clearly due to the form of administration. Esterified compounds have a high affinity to stay stored in fatty tissues. While we can accurately estimate the time frame it will take for a given dose to enter circulation from an injection site, we cannot know for sure that 100% of the steroid will have been metabolized at any given point. Small amounts may indeed be stubborn in leaving fatty tissue, particularly after heavy, longer-term use. Some quantity of nandrolone decanoate may therefore be left to sporadically enter into the blood stream many months after use. This process may be further aggravated when dieting for a show, a time when body fat stores are being actively depleted (possibly freeing more steroid). This has no doubt been the cause for many unexpected positives on a drug screen. The fact that nandrolone has been isolated as the "hands-off" injectable for the drug tested athlete is most likely due to its popularity (and therefore common appearance on drug screens). The same risk would of course hold true for other long chain esterified injectables such as Equipoise, and Primobolan.
Those not worried about drug screens are likely to find the low water retention and good effect of this drug favorable for use in pre-contest cutting stacks. A combination of Deca and Winstrol during the weeks/months leading up to a show for example, is noted to greatly enhance to look of muscularity and definition. A strong non-aromatizing androgen like Halotestin or trenbolone could be further added, providing an enhanced level of hardness and density to the muscles. Being an acceptable anabolic, Deca can also be incorporated into bulk cycles with good results. The classic Deca and Dianabol cycle has been a basic for decades, and always seems to provide excellent muscle growth. A stronger androgen such as Anadrol or testosterone could also be substituted, producing greater results. When mixed with Deca, the androgen dosage can be kept lower than if used alone, hopefully making the cycle more comfortable. Additionally one may choose to continue Deca for a number of few weeks after the androgen has been stopped. This will hopefully harden up some of the bloat produced by the androgen, giving a more quality appearance. Remember that endogenous testosterone production will not resume during Deca therapy, and ancillaries are likewise still needed.
Wednesday, July 4, 2007
Equipoise (boldenone undecylenate)
Equipoise (boldenone undecylenate)
Quick overview:
Active Life: 14-16 days
Drug Class: Anabolic/Androgenic Steroid (for injection)
Average Dose: Men 400-600 mg/week......Women 50-150 mg/week
Acne: Rare
Water Retention: Low
High Blood Pressure: Rare
Liver Toxic: No
Aromatization: Some, about 50% less than testosterone
DHT Conversion: Low
Decrease HPTA function: Moderate
Equipoise® is the popular brand name for the veterinary injectable steroid boldenone undecylenate. It is a derivative of testosterone, which exhibits strong anabolic and moderately androgenic properties. The undecylenate ester greatly extends the activity of the drug (the undecylenate ester is only one carbon atom longer than decanoate), so that clinically injections would need to be repeated every three or four weeks. In the veterinary feild Equipoise is most commonly used on horses, exhibiting a pronounced effect on lean bodyweight, appetite and general disposition of the animal. As with all steroids, this compound shows a marked ability for increasing red blood cell production. In recent years this compound has become a favorite among athletes. Many consider it an ideal replacement to Deca-Durabolin.
The side effects of Equipoise are generally mild. The structure of boldenone does allow it to convert into estrogen, but it does not have an extremely high affinity to do so. If we look at aromatization studies, they suggest that its rate of estrogen conversion should be about half that of testosterone's. Water retention with this drug would therefore be slightly higher than that with Deca-Durabolin (with an estimated 20% conversion), but much less than we would find with a stronger compound as Testosterone. While there is still a chance of encountering an estrogen related side effect as such when using Equipoise, problems are usually not encountered at a moderate dosage level. Gynecomastia might become a problem, but usually only with very sensitive individuals or (again) with those using higher dosages. If estrogenic effects become a problem, the addition of Nolvadex should of course make the cycle more tolerable. An anti-aromatase such as Arimidex, Femara, or Amonasin would be a stronger option, however probably not necessary with such a mild drug.
Although typically dosage related, Equipoise can also produce distinct androgenic side effects. Oily skin, acne, increased aggression and hair loss are all possible with this compound. Women find this drug quite comfortable, virilization symptoms usually unheard of when taken at low doses. Boldenone does reduce to a more potent androgen (dihydroboldenone) via the 5alpha reductase enzyme (which produces DHT from testosterone), however its affinity for this interaction in the human body is low to nonexistent. Therefore the reductase inhibitor Proscar would not be of much use with Equipoise, as it would be blocking what is at best an insignificant path of metabolism for the steroid. Although this drug is relatively mild, it still has a depressive effect on endogenous testosterone levels, therefore a proper post cycle therapy HCG and Clomid/Nolvadex is needed at the conclusion of each cycle to avoid a "crash". A waiting time of around 3 weeks is required before starting PCT, enabling enough of the drug to clear one's system to make PCT effective.
In order to maintain stable blood levels, Equipoise should be injected at least once per week. It is most commonly used at a dosage of 400-600mg per week for men, 50-150 mg per week for women.
Equipoise is not a rapid mass builder, but will provide a slow but steady gain of strength and quality muscle mass. The most positive effects of this drug are seen when it is used for longer cycles, usually lasting at least 10 weeks in length. The muscle gained should not be the smooth bulk seen with androgens, but instead a very defined and solid look. Since water bloat is not contributing greatly to the diameter of the muscle, much of the size gained on a cycle of Equipoise can be retained after the drug has been discontinued. It is interesting to note that structurally Equipoise and the classic bulking drug Dianabol are almost identical. In the case of Equipoise the compound uses a l7beta ester (undecylenate), while Dianabol is 17 alpha alkylated. Aside from that difference, the drugs are basically the same. Of course they act quite differently in the body, which goes to show the 17-methylation effects more than just the oral efficancy of a steroid.
As discussed earlier, Equipoise is a very versatile compound. We can create a number of drug combinations with it depending on the desired result. For mass, one may want to stack it with Anadrol or an injectable testosterone. The result should be an incredible gain of muscle size and strength, without the same intensity of side effects if using the androgen (at a higher dose) alone. When used in a cutting cycle, muscle hardness and density can be greatly improved when combining Equipoise with a non-aromatizable steroid such as trenbolone acetate, Halotestin, or Winstrol. For some however, even the low buildup of estrogen associated with this compound is enough to relegate its use to bulking cycles only.
Equipoise is not an ideal steroid for the drug tested athlete however. This drug has the tendency to produce detectable metabolites in the urine months after use, a worry most commonly associated with Deca-Durabolin. This is of course due to the high oil solubility of long chain esterified injectable steroids, a property which enables the drug to remain deposited in fatty tissues for extended periods of time. While this will reliably slow the release of steroid into the blood stream, it also allows small residual amounts to remain present in the body far after the initial injection. The release of stubborn stores of hormone would no doubt also be enhanced around contest time, a period when the athlete drastically attempts to mobilize unwanted body fat. If enough were used in the off-season, the athlete may actually fail a drug screen for boldenone although many months may have past since the drug was last injected.
Quick overview:
Active Life: 14-16 days
Drug Class: Anabolic/Androgenic Steroid (for injection)
Average Dose: Men 400-600 mg/week......Women 50-150 mg/week
Acne: Rare
Water Retention: Low
High Blood Pressure: Rare
Liver Toxic: No
Aromatization: Some, about 50% less than testosterone
DHT Conversion: Low
Decrease HPTA function: Moderate
Equipoise® is the popular brand name for the veterinary injectable steroid boldenone undecylenate. It is a derivative of testosterone, which exhibits strong anabolic and moderately androgenic properties. The undecylenate ester greatly extends the activity of the drug (the undecylenate ester is only one carbon atom longer than decanoate), so that clinically injections would need to be repeated every three or four weeks. In the veterinary feild Equipoise is most commonly used on horses, exhibiting a pronounced effect on lean bodyweight, appetite and general disposition of the animal. As with all steroids, this compound shows a marked ability for increasing red blood cell production. In recent years this compound has become a favorite among athletes. Many consider it an ideal replacement to Deca-Durabolin.
The side effects of Equipoise are generally mild. The structure of boldenone does allow it to convert into estrogen, but it does not have an extremely high affinity to do so. If we look at aromatization studies, they suggest that its rate of estrogen conversion should be about half that of testosterone's. Water retention with this drug would therefore be slightly higher than that with Deca-Durabolin (with an estimated 20% conversion), but much less than we would find with a stronger compound as Testosterone. While there is still a chance of encountering an estrogen related side effect as such when using Equipoise, problems are usually not encountered at a moderate dosage level. Gynecomastia might become a problem, but usually only with very sensitive individuals or (again) with those using higher dosages. If estrogenic effects become a problem, the addition of Nolvadex should of course make the cycle more tolerable. An anti-aromatase such as Arimidex, Femara, or Amonasin would be a stronger option, however probably not necessary with such a mild drug.
Although typically dosage related, Equipoise can also produce distinct androgenic side effects. Oily skin, acne, increased aggression and hair loss are all possible with this compound. Women find this drug quite comfortable, virilization symptoms usually unheard of when taken at low doses. Boldenone does reduce to a more potent androgen (dihydroboldenone) via the 5alpha reductase enzyme (which produces DHT from testosterone), however its affinity for this interaction in the human body is low to nonexistent. Therefore the reductase inhibitor Proscar would not be of much use with Equipoise, as it would be blocking what is at best an insignificant path of metabolism for the steroid. Although this drug is relatively mild, it still has a depressive effect on endogenous testosterone levels, therefore a proper post cycle therapy HCG and Clomid/Nolvadex is needed at the conclusion of each cycle to avoid a "crash". A waiting time of around 3 weeks is required before starting PCT, enabling enough of the drug to clear one's system to make PCT effective.
In order to maintain stable blood levels, Equipoise should be injected at least once per week. It is most commonly used at a dosage of 400-600mg per week for men, 50-150 mg per week for women.
Equipoise is not a rapid mass builder, but will provide a slow but steady gain of strength and quality muscle mass. The most positive effects of this drug are seen when it is used for longer cycles, usually lasting at least 10 weeks in length. The muscle gained should not be the smooth bulk seen with androgens, but instead a very defined and solid look. Since water bloat is not contributing greatly to the diameter of the muscle, much of the size gained on a cycle of Equipoise can be retained after the drug has been discontinued. It is interesting to note that structurally Equipoise and the classic bulking drug Dianabol are almost identical. In the case of Equipoise the compound uses a l7beta ester (undecylenate), while Dianabol is 17 alpha alkylated. Aside from that difference, the drugs are basically the same. Of course they act quite differently in the body, which goes to show the 17-methylation effects more than just the oral efficancy of a steroid.
As discussed earlier, Equipoise is a very versatile compound. We can create a number of drug combinations with it depending on the desired result. For mass, one may want to stack it with Anadrol or an injectable testosterone. The result should be an incredible gain of muscle size and strength, without the same intensity of side effects if using the androgen (at a higher dose) alone. When used in a cutting cycle, muscle hardness and density can be greatly improved when combining Equipoise with a non-aromatizable steroid such as trenbolone acetate, Halotestin, or Winstrol. For some however, even the low buildup of estrogen associated with this compound is enough to relegate its use to bulking cycles only.
Equipoise is not an ideal steroid for the drug tested athlete however. This drug has the tendency to produce detectable metabolites in the urine months after use, a worry most commonly associated with Deca-Durabolin. This is of course due to the high oil solubility of long chain esterified injectable steroids, a property which enables the drug to remain deposited in fatty tissues for extended periods of time. While this will reliably slow the release of steroid into the blood stream, it also allows small residual amounts to remain present in the body far after the initial injection. The release of stubborn stores of hormone would no doubt also be enhanced around contest time, a period when the athlete drastically attempts to mobilize unwanted body fat. If enough were used in the off-season, the athlete may actually fail a drug screen for boldenone although many months may have past since the drug was last injected.
Tuesday, July 3, 2007
Winstrol (stanozolol)
Winstrol (stanozolol) Winstrol (stanozolol) Quick overview:
Active Life: around 48 hours
Drug Class: Anabolic/Androgenic Steroid (for injection or oral)
Average Dose: Men 50-100 mg/day.....Women 25-50 mg/week
Acne: Rare
Water Retention: Rare
High Blood Pressure: Rare
Liver Toxic: Yes, it is a 17AA steroid
Aromatization: No, it is a DHT derivative
DHT Conversion: None
Decrease HPTA function: Low Winstrol is a popular brand name for the anabolic steroid stanozolol. This compound is a derivative of dihydrotestosterone, although its activity is much milder than this androgen in nature. It is technically classified as an anabolic steroid, shown to exhibit a slightly greater tendency for muscle growth than androgenic activity in early studies. While dihydrotestosterone really only provides androgenic side effects when administered, stanozolol instead provides quality muscle growth. The anabolic properties of this substance are still mild in comparison to many stronger compounds, but it is still a ggod, reliable builder of muscle. Its anabolic properties could even be comparable to Dianabol, but Winstrol does not have the same tendency for water retention. Stanozolol also contains the same c17 methylation we see with Dianabol, an alteration used so that oral administration is possible. To spite this design however, there are many injectable versions of this steroid produced.
Since stanozolol is not capable of converting into estrogen, an anti-estrogen is not necessary when using this steroid, gynecomastia is not a concern even among the most sensitive individuals. Since estrogen is also the cause of water retention, instead of bulk look, Winstrol produces a lean, quality look with no fear of excess subcutaneous fluid retention. This makes it a great steroid to use during cutting cycles, when water and fat retention are a major concern. It is also very popular among athletes in combination strength/speed sports such as Track and Field.
The usual dosage for men is 35-75mg per day for the tablets and 25-50mg per day with the injectable version. It is often combined with other steroids depending on the desired result. For bulking purposes, a stronger androgen like testosterone, Dianabol or Anadrol is usually added. Here Winstrol will balance out the cycle a bit, giving us good anabolic effect with lower overall estrogenic activity than if taking such steroids alone. The result should be a considerable gain in new muscle mass, with a more comfortable level of water and fat retention. For cutting phases Winstrol can be combined with a non-aromatizing androgen such as trenbolone or Halotestin. Such combinations should help bring about the strongly defined, hard look of muscularity so sought after among bodybuilders. Older, more sensitive individuals can add compounds like Primobolan, Deca-Durabolin or Equipoise when wishing to stack this steroid. Here they should see good results and fewer side effects than with standard androgen therapies. Women usually take around 5-10mg daily. Although female athletes usually find stanozolol very tolerable, the injectable version is usually off limits.
With the structural (c17-AA) alteration, the tablets will also place a higher level of stress on the liver than the injectable (which avoids the "first pass"). During longer or higher dosed cycles, liver values should therefore be watched closely through regular blood work. Although less common, there is still a possibility of liver damage occuring with the injectable form. While it does not enter the body through the liver, it is still broken down by it, providing a lower (but more continuous) level of stress. Such stress would of course be increased with the addition of other c17-AA oral compounds to a cycle of Winstrol. When using such combinations, cautious users would make every effort to limit the length of the cycle (preferably 6 to 8 weeks) and take some form of liver protectants. It should also be noted that both versions of Winstrol have been linked to strong adverse changes in HDL/LDL cholesterol levels. This side effect is common with anabolic steroid therapy, and obviously can become a health concern as the dose/duration of intake increase above normal. The oral version should have a greater impact on cholesterol values than the injectable due to the method of administration, and may therefore be the worse choice of the two for those concerned and this side effect.
The oral use of stanozolol can also have a profound impact on levels of SHBG (sex hormone-binding globulin). This is a characteristic of all anabolic/androgenic steroids, however its potency and form of administration make Winstrol particularly noteworthy in this regard. Since plasma binding proteins such as SHBG act to temporarily constrain steroid hormones from exerting activity, this effect would provide a greater percentage of free (unbound) steroid hormone in the body. This may amount to an effective mechanism in which stanozolol could increase the potency of a concurrently used steroid. To further this purpose one could also addition Proviron, which has an extremely high affinity for SHBG. This affinity may cause Proviron to displace other weaker substrates for SHBG (such as testosterone), another mechanism in which the free hormone level may be increased. Adding Winstrol and Proviron to your next testosterone cycle may therefore prove very useful,, markedly enhancing the free state of this potent muscle building androgen.
Active Life: around 48 hours
Drug Class: Anabolic/Androgenic Steroid (for injection or oral)
Average Dose: Men 50-100 mg/day.....Women 25-50 mg/week
Acne: Rare
Water Retention: Rare
High Blood Pressure: Rare
Liver Toxic: Yes, it is a 17AA steroid
Aromatization: No, it is a DHT derivative
DHT Conversion: None
Decrease HPTA function: Low Winstrol is a popular brand name for the anabolic steroid stanozolol. This compound is a derivative of dihydrotestosterone, although its activity is much milder than this androgen in nature. It is technically classified as an anabolic steroid, shown to exhibit a slightly greater tendency for muscle growth than androgenic activity in early studies. While dihydrotestosterone really only provides androgenic side effects when administered, stanozolol instead provides quality muscle growth. The anabolic properties of this substance are still mild in comparison to many stronger compounds, but it is still a ggod, reliable builder of muscle. Its anabolic properties could even be comparable to Dianabol, but Winstrol does not have the same tendency for water retention. Stanozolol also contains the same c17 methylation we see with Dianabol, an alteration used so that oral administration is possible. To spite this design however, there are many injectable versions of this steroid produced.
Since stanozolol is not capable of converting into estrogen, an anti-estrogen is not necessary when using this steroid, gynecomastia is not a concern even among the most sensitive individuals. Since estrogen is also the cause of water retention, instead of bulk look, Winstrol produces a lean, quality look with no fear of excess subcutaneous fluid retention. This makes it a great steroid to use during cutting cycles, when water and fat retention are a major concern. It is also very popular among athletes in combination strength/speed sports such as Track and Field.
The usual dosage for men is 35-75mg per day for the tablets and 25-50mg per day with the injectable version. It is often combined with other steroids depending on the desired result. For bulking purposes, a stronger androgen like testosterone, Dianabol or Anadrol is usually added. Here Winstrol will balance out the cycle a bit, giving us good anabolic effect with lower overall estrogenic activity than if taking such steroids alone. The result should be a considerable gain in new muscle mass, with a more comfortable level of water and fat retention. For cutting phases Winstrol can be combined with a non-aromatizing androgen such as trenbolone or Halotestin. Such combinations should help bring about the strongly defined, hard look of muscularity so sought after among bodybuilders. Older, more sensitive individuals can add compounds like Primobolan, Deca-Durabolin or Equipoise when wishing to stack this steroid. Here they should see good results and fewer side effects than with standard androgen therapies. Women usually take around 5-10mg daily. Although female athletes usually find stanozolol very tolerable, the injectable version is usually off limits.
With the structural (c17-AA) alteration, the tablets will also place a higher level of stress on the liver than the injectable (which avoids the "first pass"). During longer or higher dosed cycles, liver values should therefore be watched closely through regular blood work. Although less common, there is still a possibility of liver damage occuring with the injectable form. While it does not enter the body through the liver, it is still broken down by it, providing a lower (but more continuous) level of stress. Such stress would of course be increased with the addition of other c17-AA oral compounds to a cycle of Winstrol. When using such combinations, cautious users would make every effort to limit the length of the cycle (preferably 6 to 8 weeks) and take some form of liver protectants. It should also be noted that both versions of Winstrol have been linked to strong adverse changes in HDL/LDL cholesterol levels. This side effect is common with anabolic steroid therapy, and obviously can become a health concern as the dose/duration of intake increase above normal. The oral version should have a greater impact on cholesterol values than the injectable due to the method of administration, and may therefore be the worse choice of the two for those concerned and this side effect.
The oral use of stanozolol can also have a profound impact on levels of SHBG (sex hormone-binding globulin). This is a characteristic of all anabolic/androgenic steroids, however its potency and form of administration make Winstrol particularly noteworthy in this regard. Since plasma binding proteins such as SHBG act to temporarily constrain steroid hormones from exerting activity, this effect would provide a greater percentage of free (unbound) steroid hormone in the body. This may amount to an effective mechanism in which stanozolol could increase the potency of a concurrently used steroid. To further this purpose one could also addition Proviron, which has an extremely high affinity for SHBG. This affinity may cause Proviron to displace other weaker substrates for SHBG (such as testosterone), another mechanism in which the free hormone level may be increased. Adding Winstrol and Proviron to your next testosterone cycle may therefore prove very useful,, markedly enhancing the free state of this potent muscle building androgen.
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