Tuesday, February 27, 2007

Dianabol (methandrostenolone)

Dianabol (methandrostenolone)


Quick overview:


Active Life: 6-8 hours
Drug Class: Anabolic/Androgenic Steroid (Oral)
Average Dose: Men 15-50 mg/day......Women 5-10 mg/day
Acne: Yes, especially in higher dosages
Water Retention: Yes, similar to testosterone
dianabol informationHigh Blood Pressure: Yes
Liver Toxic: Yes
Aromatization: Yes
DHT Conversion: No
Decrease HPTA function: Yes, dose and cycle length dependant


Dianabol is the old Ciba brand name for the oral steroid methandrostenolone. It is a derivative of testosterone, exhibiting strong anabolic and moderate androgenic properties. This compound was first made available in 1960, and it quickly became the most favored and widely used anabolic steroid in all forms of athletics. This is likely due to the fact that it is both easy to use and extremely effective. In the U.S. Dianabol production had meteoric history, exploding for quite some time, then quickly dropping out of sight. Many were nervous in the late 80's when the last of the U.S. generics were removed from pharmacy shelves, the medical community finding no legitimate use for the drug anymore. But the fact that Dianabol has been off the U.S. market for over 10 years now has not cut its popularity. It remains the most commonly used black market oral steroid in the U.S. As long as there are countries manufacturing this steroid, it will probably remain so.

Similar to testosterone and Anadrol 50, Dianabol is a potent steroid, but also one which brings about noticeable side effects. For starters methandrostenolone is quite estrogenic. Gynecomastia is often a concern during treatment, and may present itself quite early into a cycle (particularly when higher doses are used). At the same time water retention can become a pronounced problem, causing a notable loss of muscle definition as both subcutaneous water and fat build. Sensitive individuals may therefore want to keep the estrogen under control with the addition of an anti-estrogen such as Nolvadex and/or Proviron. The stronger drugs Arimidex, Femara, or Aromasin (antiaromatase) would be a better choice if available.

In addition, androgenic side effects are common with this substance, and may include bouts of oily skin, acne and body/facial hair growth. Aggression may also be increased with a potent steroid such as this, so it would be wise not to let your disposition change for the worse during a cycle. With Dianabol there is also the possibility of aggravating a male pattern baldness condition. Sensitive individuals may therefore wish to avoid this drug and opt for a milder anabolic such as Deca-Durabolin. While Dianabol does convert to a more potent steroid via interaction with the 5-alpha reductase anzyme (the same enzyme responsible for converting testosterone to dihydrotestosterone), it has extremely little affinity to do so in the human body's. The androgenic metabolite 5alpha dihydromethandrostenolone is therefore produced only in trace amounts at best. Therefore the use of Proscar/Propecia would serve no real purpose.

Being moderately androgenic, Dianabol is really only a popular steroid with men. When used by women, strong virilization symptoms are of course a possible result. Some do however experiment with it, and find low doses (5mg) of this steroid extremely powerful for new muscle growth. Whenever taken, Dianabol will produce exceptional mass and strength gains. It's effectiveness is often compared to other strong steroids like testosterone and Anadrol 50, and it is likewise a popular choice for bulking purposes. A daily dosage of 20-40mg is enough to give almost anybody dramatic results. Some do venture much higher in dosage, but this practice usually leads to a more profound incidence of side effects. It additionally combines well with a number of other steroids. It is noted to mix particularly well with the mild anabolic Deca-Durabolin. Together one can expect an exceptional muscle and strength gains, with side effects not much worse than one would expect from Dianabol alone. For all out mass, a long acting testosterone ester like enanthate can be used. With the similarly high estrogenic/androgenic properties of this androgen, side effects may be extreme with such a combination however. Gains would be great as well, which usually makes such an endeavor worthwhile to the user. As discussed earlier, ancillary drugs can be added to reduce the side effects associated with this kind of cycle.

In order to withstand oral administration, this compound is c17 alpha alkylated. We know that this alteration protects the drug from being deactivation by the liver (allowing nearly all of the drug entry into the bloodstream), however it can also be toxic to this organ. Prolonged exposure to c17 alpha alkylated substances can result in actual damage, possibly even the development of certain kinds of cancer. To be safe one might want to visit the doctor a couple of times during each cycle to keep an eye on their liver enzyme values. Cycles should also be kept short, usually less than 8 weeks long to avoid doing any noticeable damage. Jaundice (bile duct obstruction) is usually the first visible sign of liver trouble, and should be looked out for. This condition produces an unusual yellowing of the skin, as the body has trouble processing bilirubin. In addition to the skin, the whites of the eyes may also yellow, a clear indicator of trouble. Should this occur the drug should be discontinued immediately and a doctor visited. This is usually a point where further, permanent damage can be avoided.

Sunday, February 25, 2007

Deca-Durabolin® (nandrolone decanoate)

Deca-Durabolin® (nandrolone decanoate)


Quick overview:


Active Life: 14-16 days
Drug Class: Anabolic/Androgenic Steroid (injectable)
Average Dose: Men 300-800 mg/week.....Women 50-100 mg/week
Acne: Yes, in higher dosages or sensitive individuals
Water Retention: Yes, but less than testosterone
High Blood Pressure: Dose depandant
Liver Toxic: No
Aromatization: Low, converts to less active norestrogens
DHT Conversion: No, converts to NOR-DHT with low activity
Decrease HPTA function: Yes, extreme
Other Info: Highly anabolic/moderate androgenic effects


Deca-Durabolin® is the Organon brand name for the injectable steroid nandrolone decanoate. This compound came around early in the wave of commercial steroid development, first being made available as a prescription medication in 1962.

World wide "Deca" is one of the most widely used anabolic steroids. Its popularity is due to the simple fact that it exhibits many very favorable properties. Structurally nandrolone is very similar to testosterone, although it lacks a carbon atom at the 19th position (hence its other name 19-nortestosterone). The resulting structure is a steroid that exhibits much weaker androgenic properties than testosterone. Of primary interest is the fact that nandrolone will not break down to a more potent metabolite in androgen target tissues. You may remember this is a significant problem with testosterone. Although nandrolone does undergo reduction via the same (5-alpha reductase) enzyme that produces DHT from testosterone, the result in this case is dihydronandrolone. This metabolite is weaker than the parent nandroloness, and is far less likely to cause unwanted androgenic side effects. Strong occurrences of oily skin, acne, body/facial hair growth and hair loss occur very rarely. It is however possible for androgenic activity to become apparent with this as any steroid, but with nandrolone higher than normal doses are usually responsible.

Nandrolone also show an extremely lower tendency for estrogen conversion. For comparison, the rate has been estimated to be only about 20% of that seen with testosterones. This is because while the liver can convert nandrolone to estradiol, in other more active sites of steroid aromatization such as adipose tissue nandrolone is far less open to this process'. Consequently estrogen related side effects are a much lower concern with this drug. An anti-estrogen is likewise rarely needed with Deca, gynecomastia only a worry among sensitive individuals. At the same time water retention is not a usual concern. This effect can occur however, but is most often related to higher dosages. The addition of Proviron and/or Nolvadex should prove sufficient enough to significantly reduce any occurrence. Clearly Deca is a very safe choice among steroids. Actually, many consider it to be the best overall steroid for a man to use when weighing the side effects and results. It should also be noted that in HIV studies, Deca has been shown not only to be effective at safely bringing up the lean body weight of patient, but also to be beneficial to the immune system.

It is of note however that nandrolone is believed to have some activity as a progestin in the body. Although progesterone is a c-19 steroid, removal of this group as in 19-norprogesterone creates a hormone with greater binding affinity for its corresponding receptor. Sharing this trait, many 19-nor anabolic steroids are shown to have some affinity for the progesterone receptor as well. This can lead to some progestin-like activity in the body, and may intensify related side effects. The side effects associated with progesterone are actually quite similar to those of estrogen, including negative feedback inhibition of testosterone production, enhanced rate of fat storage and possibly gynecomastia. Many believe the progestin activity of Deca notably contributes to suppression of testosterone synthesis, which can be marked despite a low tendency for estrogen conversion.

Deca is not known as a very "fast" builder. The muscle building effect of this drug is quite noticeable, but not dramatic. The slow onset and mild properties of this steroid therefore make it more suited for cycles with a longer duration. In general one can expect to gain muscle weight at about half the rate of that with an equal amount of testosterone. A cycle lasting eight to twelve weeks seems to make the most sense, expecting to elicit a slow, even gain of quality mass. Although active in the body for much longer, Deca is usually injected once or twice per week. The dosage for men is usually in the range of 300-600mg/week. If looking to be specific, it is believed that Deca will exhibit its optimal effect (best gain/side effect ratio) at around 2mg per pound of lean bodyweight/weekly. Deca is also a popular steroid among female bodybuilders. They take a much lower dosage on average than men of course, usually around 50mg weekly. Although only slightly androgenic, women are occasionally confronted with virilization symptoms when taking this compound. Should this become a concern, the shorter acting nandrolone Durabolin would be a safer option. This drug stays active for only a few days, greatly reducing the impact of androgenic buildup if withdrawal were indicated.

Endogenous testosterone levels can be a concern with Deca-Durabolin, especially after long cycles. It is therefore mandatory to incorporate ancillary drugs at the conclusion of therapy. An estrogen antagonist such as Clomid or Nolvadex is therefore commonly used for a few weeks. These both provide a good level of testosterone stimulation, although they may take a couple of weeks to show the best effect. HCG injections could be added for extra reassurance, acting to rapidly restore the normal ability of the testes to respond to the resumed release of gonadotropins. For this purpose one could administer three injections of 2500-50001.U., spaced five days apart. After which point the antagonist is continued alone for a few more weeks in an effort to stabilize the production of testosterone. Remember not to begin post cycle therapy (PCT) until after Deca has been withdrawn for around three weeks. Deca stays active for quite some time so the ancillary drugs will not be able to exhibit their optimal effect when the steroid is still being released into the bloodstream. The major drawback for competitive purposes is that in many cases nandrolone metabolites will be detectable in a drug screen for up to a year (or more) after use. This is clearly due to the form of administration. Esterified compounds have a high affinity to stay stored in fatty tissues. While we can accurately estimate the time frame it will take for a given dose to enter circulation from an injection site, we cannot know for sure that 100% of the steroid will have been metabolized at any given point. Small amounts may indeed be stubborn in leaving fatty tissue, particularly after heavy, longer-term use. Some quantity of nandrolone decanoate may therefore be left to sporadically enter into the blood stream many months after use. This process may be further aggravated when dieting for a show, a time when body fat stores are being actively depleted (possibly freeing more steroid). This has no doubt been the cause for many unexpected positives on a drug screen. The fact that nandrolone has been isolated as the "hands-off" injectable for the drug tested athlete is most likely due to its popularity (and therefore common appearance on drug screens). The same risk would of course hold true for other long chain esterified injectables such as Equipoise, and Primobolan.

Those not worried about drug screens are likely to find the low water retention and good effect of this drug favorable for use in pre-contest cutting stacks. A combination of Deca and Winstrol during the weeks/months leading up to a show for example, is noted to greatly enhance to look of muscularity and definition. A strong non-aromatizing androgen like Halotestin or trenbolone could be further added, providing an enhanced level of hardness and density to the muscles. Being an acceptable anabolic, Deca can also be incorporated into bulk cycles with good results. The classic Deca and Dianabol cycle has been a basic for decades, and always seems to provide excellent muscle growth. A stronger androgen such as Anadrol or testosterone could also be substituted, producing greater results. When mixed with Deca, the androgen dosage can be kept lower than if used alone, hopefully making the cycle more comfortable. Additionally one may choose to continue Deca for a number of few weeks after the androgen has been stopped. This will hopefully harden up some of the bloat produced by the androgen, giving a more quality appearance. Remember that endogenous testosterone production will not resume during Deca therapy, and ancillaries are likewise still needed.

Saturday, February 24, 2007

Clomid

Clomid

Strong gonadotropin stimulator/mild anti-estrogenClomiphene is a synthetic estrogen clinically administered to help womenovulate. Bodybuilders, (male) following AAS cycles, seeking to jump start naturaltestosterone production (or those that were simply seeking a natural testosterone spike)have used this drug with great success
clomid

Clomid tablet box and blister package - more commonly found in Liquid form

Clomiphene increases activity in thehypothalamus-pituitary-gonadol axis by stimulating the release of more gondotropin fromthe pituitary gland. Therefore, a higher/faster level of LH (luteinizing hormone) and FSH(follicle stimulating hormone) results. This creates a signal to the leydig cells in the testeswhich in turn produce more testosterone and sperm. Normally with Clomiphene this took5-15 days. Most started with 50-mg twice daily for about 5 days, then reduced intake to50 mg once a day for 5-10 more days. Due to Clomiphene providing a fast response time,I felt it was often beneficial to use a dosage of 100 mg total daily for 5 days, mid-cycleduring longer AAS protocols. This drug was seldom utilized for longer than 15 dayscontinuously simply due to it being unnecessary. The goal was to normalize testosteroneproduction post AAS cycle as quickly as possible so as to minimize post-cycle strengthand mass loss. Not create dependency.HCG was combined with Clomiphene (Clomid) sometimes, or Clomiphene wasused after HCG administration. This is because Clomiphene acts by affecting thehypothalamus and pituitary (hypophysis) and regenerating the whole regulating system,while HCG only "imitates" LH, thus stimulating the leydig cells in the testes to producenatural testosterone. (*Also see HCG)*Some may wonder about Clomiphene being a synthetic estrogen. Yes, it is, but itworks as an anti-estrogen. This is due to the fact that Clomiphene has a very low estrogeniceffect. This means stronger and more active estrogen, such as those formed during thearomatization of many androgenic steroids, are blocked out of the receptor-site and lessestrogenic activity results; less gyno, less water retention. Clomiphene was by no means aseffective as Novladex or Proviron for estrogen suppression, but post-cycle it helped greatly.

Reported Characteristics

Active Life: about 8-12 hours
Drug Class: Synthetic estrogen/HPTA stimulator (Oral)
Average Reported Dosage: Men 50-100 mg daily
Water Retention: No
High Blood Pressure: Rare
Aromatization: None
Liver Toxic: Low, seldom reported.


TRADE NAMES

CLOMID 50MG TABS (Egis, Greece)
CLOMID 50MG TABS (International Pharmaceuticals)
ARDOMON 50 MG TABS
CLOMID 50 MG TABS
CLOMIPHEN-MERCK 50MG TABS
CLOSTIBEGYT 50MG TABS
CLOMIFEN 50MG TABS
CLOMIFEN 25MG CAPS
OMNIFIN 50 MG TABS
TOKORMON 50MG TABS

Thursday, February 22, 2007

Testosterone propionate

Testosterone propionate


Quick overview:


Active Life: 2-3 days
Drug Class: Anabolic/Androgenic Steroid (for injection)
Average Dose: Men 50-200 mg/day
Acne: Yes
Water Retention: Yes, high
High Blood Pressure: Yes
Liver Toxic: Low
Aromatization:Yes, high
DHT Conversion: Yes, high
Decrease HPTA function: Yes, severe


Testosterone propionate is a commonly manufactured, oil-based injectable testosterone compound. The propionate ester will slow the rate in which the steroid is released from the injection site, but only for a few days. Testosterone propionate is therefore much faster acting than other testosterone esters such as cypionate or enanthate, and requires a much more frequent dosing schedule, in order to maintain stable blood levels. While cypionate and enanthate are injected on a weekly or bi-weekly basis, propionate is usually injected every second. The propionate ester can be very irritating to the site of injection. In fact, many sensitive individuals choose to stay away from this steroid completely, their body reacting with a pronounced soreness and low-grade fever that may last for a few days.

Those who do not mind frequent injections will find propionate to be quite an effective steroid. As with all testosterones, it is a powerful mass drug, capable of producing rapid gains in size and strength. At the same time the buildup of estrogen and DHT (dihydrotestosterone) will be pronounced, so typical testosterone side effects are to be expected. Many consider propionate to be the mildest testosterone ester, and the preferred form for the dieting/cutting phases of training. Some will go so far as to say that propionate will harden the physique, while giving the user less water and fat retention than one typically expects to see with a testosterone. Realistically however, this is nonsense. The ester is removed before testosterone is active in the body, and likewise the ester cannot alter the activity of the parent steroid in any way, only slow its release. We can say that propionate might be the favored testosterone among female bodybuilders (for those who insist on testosterone use), as blood levels are easier to control with it compared to other esters. Should virilization symptoms develop, one would not wish to wait the weeks needed for testosterone concentrations to fall after a shot of enanthate for example.

During a typical cycle one will see action that is consistent with a testosterone. Users sensitive to gynecomastia and water retention may therefore need to add an anti-estrogen like Arimidex, Femara or Aromasin. Those particularly troubled by gynecomastia may find that a combination of Nolvadex and Proviron works especially well at preventing/halting this occurrence. Also unavoidable with a testosterone are androgenic side effects like oily skin, acne, increased aggression and body/facial hair growth. Those who may have a predisposition for male pattern baldness may also find that propionate will aggravate this condition. To help combat this one may choose to Propecia/Proscar, which will reduce the buildup of DHT in many androgen target tissues. This will help minimize related side effects (particularly hair loss) although it offers us no guarantees. And as with all testosterone products, propionate will also suppress endogenous testosterone production. The use of a testosterone stimulating drug like HCG and/or Clomid/Nolvadex is therefore a requirement in order to avoid enduring a post-cycle crash.

The most common dosage schedule for this compound (men) is to inject 50 to 100mg, every day or 2nd day. As with the more popular esters, the total weekly dosage would be in the range of 300-700mg. As with all testosterone compounds, this drug is most appropriately suited for bulking phases of training. Here it is most often combined with other strong agents such as Dianabol, Anadrol, or Deca-Durabolin, combinations that prove to work quite well. Propionate however is sometimes also used with nonaromatizing anabolics/androgens during cutting or dieting phases of training, a time when it's fast action and androgenic nature are also appreciated. Popular stacks include a moderate dosage of propionate with an oral anabolic like Winstrol (15-35 mg daily), Primobolan (50-150mg daily) or oxandrolone (15-30mg daily). Provided the body fat percentage is sufficiently low, the look of dense muscularity can be notably improved (barring any excess estrogen buildup from the testosterone). One could also add a non-aromatizing androgen like trenbolone or Halotestin, which should have an even more extreme effect on subcutaneous body fat and muscle hardness. Of course with the added androgen content any related side effects will become much more pronounced.

Women who absolutely must use an injectable testosterone should only use this preparation. The dosage schedule should also be more spread out for a female bodybuilder, with injections coming every 5 to 7 days. The dosage obviously would be lower as well, generally in the range of 25mg to 50mg per injection. Androgenic activity should be less pronounced with this schedule, giving blood levels time to sufficiently decrease before the drug is administered again. In order to further reduce any risks, the duration of this cycle should not exceed 8 weeks. Should a stronger anabolic effect be needed, a small amount of Durabolin (Deca-Durabolin if unavailable), Oxandrolone or Winstrol could be added. Of course the risk of noticing virilizing effects from these drugs may increase, even with the addition of a mild anabolic. Since many of the masculinizing side effects of steroid use can be irreversible, it is very important for the female athlete to monitor the dosage, duration and incidence of side effects very closely.

Some Vet companies as well as UG labs are now even producing 250mg/ml dosage vials. This dosage is more shocking than it sounds at first next to all the 250mg enanthate and now cypionate products in circulation. Testosterone propionate is less oil soluble than Testosterone enanthate or cypionate, making a high dosage more difficult to achieve. Before this the highest concentration you could find of this steroid was 100mg/ml. Reaching 250 milligrams is no doubt a result of not simply adding more steroid to one ml of oil, but increasing the alcohol content in the solution considerably as well. This makes for a much more uncomfortable solution to inject. Although admittedly the highest dose of propionate you will ever find, users have been reporting that it is also intolerably painful. Most find they have to dilute the solution with other lower dosed steroids if they are to continue using the product. This should be no a surprise I guess with a steroid that already has a reputation as being painful to inject.

Monday, February 19, 2007

Human Growth Hormone

Human Growth Hormone


Quick overview:


Active Life: Varies by injection method
Drug Class: Growth Hormone/IGF-1 Precursor (for injection)
Average Dose: Men 2-6 i.u. total daily
Acne: No
Water Retention: Rare
High Blood Pressure: Rare
Liver Toxic: No
Aromatization: No
Comments: High Anabolic/No Androgenic effects


In the human body growth hormone is produced by the pituitary gland. It exists at especially high levels during adolescence when it promotes the growth of tissues, protein deposition and the breakdown of subcutaneous fat stores. Upon maturation endogenous levels of GH decrease, but remain present in the body at a substantially lower level. In the body the actual structure of growth hormone is a sequence of 191 amino acids. Once scientists isolated this hormone, many became convinced it would exhibit exceptional therapeutic properties. It would be especially effective in cases of pituitary deficient dwarfism, the drug perhaps restoring much linear growth if administered during adolescence.

he 1980's brought about the first prepared drugs containing Human Growth Hormone. The content was taken from a biological origin, the hormone being extracted from the pituitary glands of human corpses then prepared as a medical injection. This production method was short lived however, since it was linked to the spread of a rare and fatal brain disease. Today virtually all forms of HGH are synthetically manufactured. The recombinant DNA process is very intricate; using transformed e-coli bacterial or mouse cell lines to genetically produce the hormone structure. It is highly unlikely you will ever cross the old biologically active item on the black market (such as Grorm), as all such products should now be discontinued. Here in the United States two distinctly structured compounds are being manufactured for the pharmaceutical market. The item Humatrope by Eli Lilly Labs has the correct 191 amino acid sequence while Genentech's Protropin has 192. This extra amino acid slightly increases the chance for developing an antibody reaction to the growth hormone. The 191 amino acid configuration is therefore considered more reliable, although the difference is not great. Protropin is still Anabolics 2002 considered an effective product and is prescribed regularly. Outside of the U.S., the vast majority of HGH in circulation will be the correct 191 amino acid sequence so this distinction is not a great a concern.

The use of growth hormone has been increasing in popularity among athletes, due of course to the numerous benefits associated with use. To begin with, GH stimulates growth in most body tissues, primarily due to increases in cell number rather than size. This includes skeletal muscle tissue, and with the exception of eyes and brain all other body organs. The transport of amino acids is also increased, as is the rate of protein synthesis. All of these effect are actually mediated by IGF-1 (insulin-like growth factor), a highly anabolic hormone produced in the liver and other tissues in response to growth hormone (peak levels of IGF-1 are noted approximately 20 hours after HGH administration). Growth hormone itself also stimulated triglyceride hydrolysis in adipose tissue, usually producing notable fat loss during treatment. GH also increases glucose output in the liver, and induces insulin resistance by blocking the activity of this hormone in target cells. A shift is seen where fats become a more primary source of fuel, further enhancing body fat loss.

Its growth promoting effect also seems to strengthen connective tissues, cartilage and tendons. This effect should reduce the susceptibility to injury (due to heavy weight training), and increase lifting ability (strength). HGH is also a safe drug for the "piss-test". Although its use is banned by athletic committees, there is no reliable detection method. This makes clear its attraction to (among others) professional bodybuilders, strength athletes and Olympic competitors, who are able to use this drug straight through a competition. There is talk however that a reliable test for the exogenous administration of growth hormone has been developed, and is close to being implemented. Until this happens, growth hormone will remain a highly sought after drug for the tested athlete.

But the degree in which HGH actually works for an athlete has been the topic of a long running debate. Some claim it to be the holy grail of anabolics, capable of amazing things. Able to provide incredible muscle growth and unbelievable fat loss in a very short period of time. Since it is used primarily by serious competitors who can afford such an expensive drug, a great body of myth further surrounds HGH discussion (among those personally unfamiliar). Many will state with the utmost confidence that the incredible mass of the Olympian competitors each year is 100% due to the use of HGH. Others have crossed bodybuilding materials claiming it to be a complete waste of money, an ineffective anabolic and barely worthwhile for fat loss. With its high price tag, certainly an incredibly poor buy in the face of steroids. So we have a very wide variety of opinions regarding this drug, whom should we believe?

It is first important to understand why there the results obtained from this drug seem to vary so much. A logical factor in this regard would seem to be the price of this drug. Due to the elaborate manufacturing techniques used to produce it, it is extremely costly. Even a moderately dosed cycle could cost an athlete between $75-$150 per daily dosage. Most are unable or unwilling to spend so much, and instead tinker around with low dosages of the drug. Most who have used this item extensively claim it will only be effective at higher doses. Poor results would then be expected if low amounts were used, or the drug not administered daily. If you cannot commit to the full expense of an HGH cycle, you should really not be trying to use the drug.

The average male athlete will usually need a dosage in the range of 4 to 6 I.U. per day to elicit the best results. On the low end perhaps 1 to 2 I.U. can be used daily, but this is still a considerable expense. Daily dosing is important, as HGH has a very short life span in the body. Peak blood concentrations are noted quickly (2 to 6 hours) after injection, and the hormone is cleared from the body with a half-life of only 20-30 minutes. Clearly it does not stick around very long, making stable blood levels difficult to maintain. The effects of this drug are also most pronounced when it is used for longer periods of time, often many months long. Some do use it for shorter periods, but generally only when looking for fat loss. For this purpose a cycle of at least four weeks would be used. This compound can be administered in both an intramuscular and subcutaneous injection. "Sub-Q" injections are particularly noted for producing a localized loss of fat, requiring the user to change injection points regularly to even out the effect. A general loss of fat seems to be the one characteristic most people agree on. It appears that the fat burning properties of this drug are more quickly apparent, and less dependent on high doses.

Other drugs also need to be used in conjunction with HGH in order to elicit the best results. Your body seems to require an increased amount of thyroid hormones, insulin and androgens while HGH levels are elevated (HGH therapy in fact is shown to lower thyroid and insulin levels). To begin with, the addition of thyroid hormones will greatly increase the thermogenic effectiveness of a cycle. Taking either Cytomel® or Synthroid® (prescription versions of T-3 and T-4) would seem to make the most sense (the more powerful Cytomel® is usually preferred). Insulin as well is very welcome during a cycle, used most commonly in an anabolic routine as described in this book under the insulin heading. Aside from replacing lowered insulin levels, use of this hormone is important as it can increase receptor sensitivity to IGF-1, and reduce levels of IGF binding protein-1 allowing for more free circulating IGF-1 (growth hormone itself also lowers IGF binding protein levelss'). Steroids as well prove very necessary for the full anabolic effect of GH to become evident. Particularly something with a notable androgenic component such as testosterone or trenbolone (if worried about estrogen) should be used. The added androgen is quite useful, as it promotes anabolism by enhancing muscle cell size (remember GH primarily effects cell number). Steroid use may also increase free IGF-1 via a lowering of IGF binding proteins. The combination of all of these (HGH, anabolics, insulin and T-3) proves to be the most synergistic combination, providing clearly amplified results. it is of course important to note that thyroid and insulin are particularly powerful drugs that involve a number of additional risks.

Release and action of GH and IGF-1: GHRH (growth hormone releasing hormone) and SST (somatostatin) are released by the hypothalamus to stimulate or inhibit the output of GH by the pituitary. GH has direct effects on many tissues, as well as indirect effects via the production of IGF-1. IGF-1 also causes negative feedback inhibition at the pituitary and hypothalamus. Heightened release of somatostatin affects not only the release of GH, but insulin and thyroid hormones as well.

HGH itself does carry with it some of its own risks. The most predominantly discussed side effect would be acromegaly, or a noticeable thickening of the bones (notably the feet, forehead, hands, jaw and elbows). The drug can also enlarge vital organs such as the heart and kidney, and has been linked to hypoglycemia and diabetes (presumably due to its ability to induce insulin resistance). Theoretically, overuse of this hormone can bring about a number of conditions, some life threatening. Such problems however are extremely rare. Among the many athletes using growth hormone, we have very few documented cases of a serious problem developing. When used periodically at a moderate dosage, the athlete should have little cause for worry. Of course if there are any noticeable changes in bone structure, skin texture or normal health and well being during use, HGH therapy should be completely halted.

In summary, the biggest mistake we can make with this drug is to get confused by the price tag. Even a relatively short cycle of this drug (and ancillaries) will cost in the thousand(s), not hundreds of dollars. We cannot jump to the conclusion that GH is therefore the most unbelievable anabolic. This hormone is simply very complex, and costly to manufacture (though it should be getting cheaper). If you were looking to achieve just a great mass gain the $1,000 would be better spent on steroids. Growth Hormone will not turn you into an overnight "freaky" monster and it is certainly not "the answer". Yes, it is a very effective performance enhancement tool. But it is more a tool for the competitive athlete looking for more than steroids alone can provide. There is little doubt that GH contributes considerably to the physiques and performance of many top bodybuilders and athletes. In this arena, the money spent on it is well justified, the drug obviously necessary. But outside of competitive sports it is usually not.

Sunday, February 18, 2007

Omnadren 250

Omnadren 250 (4-Testosterone Ester Blend)


Omnadren is a mixture of 4 Testosterones: 60-mg Testosterone Phenylpropionate 30-mg Testosterone Propionate 60-mg Testosterone Isohexanoate 100-mg Testosterone Hexanoate
Omnadren 250 is very popular because it is similar to Sustanon 250 but is a little cheaper in most cases Omnadren is similar to Sustanon (it was the second 4-testosterone blend on the marked), and is only different from Sustanon in that Omnadren contains Testosterone Isohexanoate and Testosterone Hexanoate, instead of Testosterone Decanoate and Isocaproate. This gave omnadren 250Omnadren a proclivity towards higher water retention rating and aromatization factor over Sustanon.The comparison is, however, still very appropriate. Counterfeit Sustanon was often simply the much cheaper test blend Omnadren.


Omnadren provides the same fast weight gain and strength build-up of any other long-estered testosterone. Unfortunately,it can also give the user a bloated appearance if an aromatase-inhibitor (such as exemestane) is not used. Typical reports from Omnadren users include increased pump, appetite, and training aggressiveness as well as an enhanced sex drive. Acne, Hairloss, and water retention are also reported, unfortunately.


Omnadren is clearly both very androgenic and vey anabolic. It is generally only considered appropriate for bulking cycles where mass and strength build-ups were desired. Commonly, it is stacked with Deca-Durabolin or Equipoise, and/or Anadrol.


Reported Characteristics
Pharmaceutical Name:Testosterone Chemical Name:4-androsten-3-one-17b-ol Cutting/Bulking:Bulking Anabolic Rating:100 Active Life: About 18 days total Drug Class: Androgenic/Anabolic Steroid (For injection) Average Reported Dosage: 125-1500MG weekly (males only) Acne: Yes Water Retention: Yes High Blood Pressure: Yes Liver Toxic: Low, except in high dosages Aromatization: Yes DHT Conversion: Yes, high Decreases HPTA function: Yes Average Price: $8/per amp

Friday, February 16, 2007

Cytomel® (liothyronine sodium)

Cytomel ® (liothyronine sodium)


Quick overview:
Drug Class: Synthetic thyroid hormoneAverage Dose: 25-100 mcg/dayComments: Significant suppression of Thyroid function during use


Cytomel® is the popularly recognized brand name for the drug liothyronine sodium. This is not an anabolic steroid but a thyroid hormone. It is used medically to treat cases of thyroid insufficiency, obesity, certain metabolic disorders and fatigue. Specifically this drug is a pharmaceutical preparation of the natural thyroid hormone triiodothyronine (T-3). When administered, Cytomel increases the patient's metabolism. The result is an increased rate of cellular activity (noted by a more rapid utilization of carbohydrates, fats and proteins). Bodybuilders are particularly attracted to this drug for its ability to burn off body excess fat. Most often utilized during contest preparation, one can greatly decrease the amount of stored fat without being forced to severely restrict calories. To this end Cytomel is commonly used in conjunction with Clenbuterol and can produce extremely dramatic results. This combination has become very popular in recent years, no doubt responsible for many "ripped" on-stage physiques. It is also noted by many that when thyroid hormones are taken in conjunction with steroids, an increased anabolic effect can be seen (noticeably greater than if the steroids are used alone). This is likely due to faster utilization of proteins by the body, increasing the rate for new muscle accumulation.


Caution should be taken if one is considering using this drug. Cytomel comes with an extensive list of warnings and precautions which are not to be ignored. Side effects include, but are not limited to, heart palpitations, agitation, shortness of breath, irregular heartbeat, sweating, nausea, headaches, and psychic/metabolic disorders. It is a powerful hormone, and one that could potentially alter the normal functioning of the body if misused. When taking Cytomel, one must remember to increase the dosage slowly. Generally one 25mcg tablet is taken on the first day, and the dosage is thereafter increased by one tablet every three of four days for a maximum dosage of 100mcg. This will help the body adjust to the increased thyroid hormone, hopefully avoiding any sudden "shock" to the system. The daily dose should also be split evenly throughout the day, in an effort to keep blood levels steadier. Women are more sensitive to the side effects of Cytomel than men, and usually choose not to take no more than 50mcg daily.
It is important to stress that a cycle should last no longer than 6 weeks and it should never be halted abruptly. As slowly as the dosage was built up it should also be lowered, one tablet every 3-4 days. Taking Cytomel for too long and/or at too high a dosage can result in a permanent thyroid deficiency. After doing such, one might need to be treated with a drug like Cytomel for life. It is also a good idea to first consult your physician and have your thyroid function tested. An undiagnosed hyperfunction would not mix well with the added hormone. An athlete should also be sure never to purchase an injectable form of the drug. It is generally an emergency room product, much too powerful for athletic use. Since T-3 is the most powerful thyroid hormone athletes are using, this is generally not the starting point for a beginner. Before using such a powerful item, it is a good idea to become familiar with a weaker substance. The highly popular Triacana is very mild, allowing the user much more latitude (from severe side effects) than Cytomel. An in-between point is Synthroid (synthetic T-4), still weaker in action than Cytomel. Once the user is ready however, the fat burning effect of this hormone can be extremely dramatic.

Tuesday, February 13, 2007

Dianabol (methandrostenolone)

Dianabol (methandrostenolone)

Quick overview:


Active Life: 6-8 hours
Drug Class: Anabolic/Androgenic Steroid (Oral)
Average Dose: Men 15-50 mg/day......Women 5-10 mg/day
Acne: Yes, especially in higher dosages
dianabol informationWater Retention: Yes, similar to testosterone
High Blood Pressure: Yes
Liver Toxic: Yes
Aromatization: Yes
DHT Conversion: No
Decrease HPTA function: Yes, dose and cycle length dependant

Dianabol is the old Ciba brand name for the oral steroid methandrostenolone. It is a derivative of testosterone, exhibiting strong anabolic and moderate androgenic properties. This compound was first made available in 1960, and it quickly became the most favored and widely used anabolic steroid in all forms of athletics. This is likely due to the fact that it is both easy to use and extremely effective. In the U.S. Dianabol production had meteoric history, exploding for quite some time, then quickly dropping out of sight. Many were nervous in the late 80's when the last of the U.S. generics were removed from pharmacy shelves, the medical community finding no legitimate use for the drug anymore. But the fact that Dianabol has been off the U.S. market for over 10 years now has not cut its popularity. It remains the most commonly used black market oral steroid in the U.S. As long as there are countries manufacturing this steroid, it will probably remain so.

Similar to testosterone and Anadrol 50, Dianabol is a potent steroid, but also one which brings about noticeable side effects. For starters methandrostenolone is quite estrogenic. Gynecomastia is often a concern during treatment, and may present itself quite early into a cycle (particularly when higher doses are used). At the same time water retention can become a pronounced problem, causing a notable loss of muscle definition as both subcutaneous water and fat build. Sensitive individuals may therefore want to keep the estrogen under control with the addition of an anti-estrogen such as Nolvadex and/or Proviron. The stronger drugs Arimidex, Femara, or Aromasin (antiaromatase) would be a better choice if available.

In addition, androgenic side effects are common with this substance, and may include bouts of oily skin, acne and body/facial hair growth. Aggression may also be increased with a potent steroid such as this, so it would be wise not to let your disposition change for the worse during a cycle. With Dianabol there is also the possibility of aggravating a male pattern baldness condition. Sensitive individuals may therefore wish to avoid this drug and opt for a milder anabolic such as Deca-Durabolin. While Dianabol does convert to a more potent steroid via interaction with the 5-alpha reductase anzyme (the same enzyme responsible for converting testosterone to dihydrotestosterone), it has extremely little affinity to do so in the human body's. The androgenic metabolite 5alpha dihydromethandrostenolone is therefore produced only in trace amounts at best. Therefore the use of Proscar/Propecia would serve no real purpose.

Being moderately androgenic, Dianabol is really only a popular steroid with men. When used by women, strong virilization symptoms are of course a possible result. Some do however experiment with it, and find low doses (5mg) of this steroid extremely powerful for new muscle growth. Whenever taken, Dianabol will produce exceptional mass and strength gains. It's effectiveness is often compared to other strong steroids like testosterone and Anadrol 50, and it is likewise a popular choice for bulking purposes. A daily dosage of 20-40mg is enough to give almost anybody dramatic results. Some do venture much higher in dosage, but this practice usually leads to a more profound incidence of side effects. It additionally combines well with a number of other steroids. It is noted to mix particularly well with the mild anabolic Deca-Durabolin. Together one can expect an exceptional muscle and strength gains, with side effects not much worse than one would expect from Dianabol alone. For all out mass, a long acting testosterone ester like enanthate can be used. With the similarly high estrogenic/androgenic properties of this androgen, side effects may be extreme with such a combination however. Gains would be great as well, which usually makes such an endeavor worthwhile to the user. As discussed earlier, ancillary drugs can be added to reduce the side effects associated with this kind of cycle.

In order to withstand oral administration, this compound is c17 alpha alkylated. We know that this alteration protects the drug from being deactivation by the liver (allowing nearly all of the drug entry into the bloodstream), however it can also be toxic to this organ. Prolonged exposure to c17 alpha alkylated substances can result in actual damage, possibly even the development of certain kinds of cancer. To be safe one might want to visit the doctor a couple of times during each cycle to keep an eye on their liver enzyme values. Cycles should also be kept short, usually less than 8 weeks long to avoid doing any noticeable damage. Jaundice (bile duct obstruction) is usually the first visible sign of liver trouble, and should be looked out for. This condition produces an unusual yellowing of the skin, as the body has trouble processing bilirubin. In addition to the skin, the whites of the eyes may also yellow, a clear indicator of trouble. Should this occur the drug should be discontinued immediately and a doctor visited. This is usually a point where further, permanent damage can be avoided.

It is also interesting to note that methandrostenolone is structurally identical to boldenone (EQ), except that it contains the added c17 alpha alkyl group discussed above. This fact makes clear the impact of altering a steroid in such a way, as these two compounds appear to act very differently in the body. The main dissimilarity seems to lie in the tendency for estrogenic side effects, which seems to be much more pronounced with Dianabol. Equipoise is known to be quite mild in this way, and users therefore commonly take this drug without any need of an anti-estrogen. Dianabol is much more estrogenic not because it is more easily aromatized, as in fact the 17 alpha methyl group and c1-2 double bond both slow the process of aromatization. The problem is that methandrostenolone converts to l7alpha methylestradiol, a more biologically active form of estrogen than regular estradiol. But Dianabol also appears to be much more potent in terms of muscle mass compared to boldenone, supporting the notion that estrogen does play an important role in anabolism. In fact boldenone and methandrostenolone differ so much in their potencies as anabolics that the two are rarely though of as related. As a result, the use of Dianabol is typically restricted to bulking phases of training while Equipoise is considered an excellent cutting or lean-mass building steroid.

The half-life of Dianabol is only about 3 to 4 hours, a relatively short time. This means that a single daily dosage schedule will produce a varying blood level, with ups and downs throughout the day. The user likewise has a choice, to either split up the tablets during the day or to take them all at one time. The usual recommendation has been to divide them and try to regulate the concentration in your blood. This however, will produce a lower peak blood level than if the tablets were taken all at once, so there may be a trade off with this option. The steroid researcher Bill Roberts also points out that a single-episode dosing schedule should have a less dramatic impact on the hypothalamic-pituitary-testicular axis, as there is a sufficient period each day where steroid hormone levels are not extremely exaggerated. I tend to doubt hormonal stability can be maintained during such a cycle however, but do notice that anecdotal evidence often still supports single daily doses to be better for overall results. Perhaps this is the better option. Since we know the blood concentration will peak about 1.5 to 3 hours after administration, we may further wonder the best time to take our tablets. It seems logical that taking the pills earlier in the day, preferably some time before training, would be optimal. This would allow a considerable number of daytime hours for an androgen rich metabolism to heighten the uptake of nutrients, especially the critical hours following training.

Monday, February 12, 2007

Winstrol (Tablets)

winstrol tablets

Winstrol (Tablets)


Winstrol Tablets Information

Alot of what holds true for the injectable version of this product (see: Winstrol Depot) also holds for the tabs. There are, however, two noticable differences between the two forms of administration. Nitrogen Retention is greater with use of the injectable version, when equal doses are administered. Paradoxically, it would seem that on a milligram for milligram basis, users have reported that oral administration of Stanozolol was more potent than the injectable produc for building muscle. This could be due to winstrol's ability to lower SHBG (Sex Hormone Binding Globulin) levels and also elevate IGF (Insulin-Like Growth Factor) above those experienced with the injectable version.

British Dragon winstrol tabs are one of the most popular versions on the market today. Women athletes commonly reported the use of Stanozolol at a dosage of 10mg daily, and I am of the opinion that women should preferentially use the injectable version when possible.
Men have found that it works well when used in 50-100mg daily doses, and stacked very efficiently with Testosterone and Nandrolone or Trenbolone.

Reported Characteristics
Pharmaceutical Name:Stanozolol Chemical Name:17-beta-hydroxy-17-methyl-5alpha-androstano[3,2-c]pyrazole Cutting/Bulking:Cutting Anabolic Rating:320 Active-Life: About 8 hours Drug Class: Anabolic/Androgenic steroid (Oral) Average Reported Dosage: Males 25-50-mg daily Women 10mg daily Acne: Possible Water Retention: No High Blood Pressure: Rare Liver Toxic: High in high oral dosages DHT Conversion: DHT-derived Decreases HPTA Function: No Average Price:Up to $1/10mg tab

TRADE NAMES:
WINSTROL 50-MG TABS (British Dragon) WINSTROL 10-MG TABS (British Dragon) WINSTROL 50-MG Tabs (International Pharmaceuticals) STANOZOLOL 5-MG TABS STANAZOLIC 6-MG CAPS

Thursday, February 8, 2007

Anadrol - Oxymetholone

anadrol 50 information


Anadrol - Oxymetholone



Steroid Profiles - Anadrol - Oxymetholone

This is an oral, methylated (17-alpha-alkylated) steroid that is both highly androgenic as well as highly anabolic. Some novice users report weight gains of up to a pound per day fpor the first 3 weeks of administration, as well as incredible strength gains. Neither is uncommon among first-time steroid users, and this type of weight gain makes Anadrol one of the most highly coveted drugs for off season mass-building cycles. Aggressiveness often increases dramatically on this compound, and that may be due to the elevation in androgen levels it provides, it's effects on the central nervous system, and it being derived from DHT (Dihydrotestosterone), which anecdotally seems to make athletes much more agressive. This last effect is often seen by the media as a negative side effect, but in a hard training (and emotionally stable) athlete, this aggressiveness often manifests itself as a stronger drive in the gym and results in more strength gained, and ultimately, more weight. Unfortunately, users of this drug also experience the negative aspects of DHT which can include excessive water retention, acne, and hairloss.
Anadrol 50 tablets by British Dragon Many people consider Anadrol a dangerous compound, but this isn't necessarily so. Anadrol was originally produced in a whopping 50mg pill, so you don't need to take many of them to get a very high dose of Oxymetholone (the drug in Anadrol). Compare this dose to Anavar which is produced in a 2.5mg pill, or Dianabol which was produced in a 5mg pill, and you'll see why Anadrol has such a reputation for being powerful. One tab is has as many milligrams as 20 of the original Anavar tabs or 20 of the original Dianabol tabs! On a milligram for milligram basis, Anadrol is no more dangerous than most oral steroids out there. You just have to remember that you get 50mgs in each tablet, and adjust your dose accordingly. Occasionally people using Anadrol get flu-like-symptoms or a headache. I personally get both, but the headache is much worse (it is probably from my bloodpressure elevating quickly). Alot of the horror stories you hear about steroids is from people abusing this one in particulat. Chris Duffy ( a now retired IFBB professional) claimed to use ten of them every day. It's no wonder that it has been linked to prostate and liver cancer, liver disease, thyroid dysfunction, leukemia, and heart disorders, and even hepatic comas. Again, this is a powerful drug, and not to be taken lightly, but is no more dangerous than many others. It will also raise your hematocrit, and commesurately your blood pressure. to where clotting time may become an issue. Since Anadrol is derived from DHT, it can cause issues in DHT-sensitivce target tissure like the scalp, prostate, and sebaceous glands. It can also cause suppression of the Hypothalamic-Pituitary-Testicular-Axis, resulting in a low sperm count, and a lowering of Leutenizing hormone, which is what signals your testes to secrete testosterone. Anadrol therapy, therefore, will lower your testosterone levels.




Women generally steer clear of Anadrol, because of it's possible virilizing effects, including clitoral enlargement, facial hair growth, deeper voice, and missed periods..
Oxymetholone is infamous for negatively effecting liver function and increasing markers of that such as SGPT and SGOT enzymes (and others) which are all hepatic indicators (indicators of liver dysfunction). Jaundice (a yellowing of the whites of the eyes and finger nails) can even occur from extended Anadrol use. As previously stated, Anadrol is a derivative of DHT, which is itself a 5-alpha-reduced version of testosterone. Some androl users have reported gyno from its use but this is unlikely to be a result of anadrol (which doesn't convert to estrogen, nor DHT, nor can it stimulate the progesterone receptor). Users of Anadrol who experience gynocomastia (the of breast tissue by males) have probably developed this condition as a result of the concurrent use of another steroid along with their Anadrol. Oxymetholone also causes edema (water retention) which could possibly be due to enhanced retention, which often causes a smoothe appearance to muscles.




Andarol'is medical use is (as with most steroids) to treat low red blood cell production, which often manifests itself as aenemia. Therefore, during administration of Anadrol, red blood cell count is increased greatly. For the hard-training athlete, this is a great benefit bnecause it meant that there is more oxygen transported to the muscles, resulting in both an incredible muscle pump as well as increased ability to do multiple sets with very heavy weights. The time needed between sets, and ability to do more sets per workout are both increased, and a reduced need for off-days from the gym is often seen as well. This increased work capacity contributes to the athlete being able to do a great deal more productive weight training sessions per cycle, and this of course contributes to their gains immeasurably.




Advanced bodybuilders and power lifters have reported excellent results with 50-200 mg per day, taken in divided doses. It's very often the drug of choice for athletes attempting to move up a weight class in bodybuilding or powerlifting. Although myself and many others have used Anadrol alone, it's not very common to do so, and it's generally stacked with something like Testosterone, and Deca Durabolin or Equipoise. By stacking it with highly anabolic compounds like them, more high quality gains are generally seen, and less of the watery/bloated look is experienced.

Reported Characteristics
Pharmaceutical Name:Oxymetholone



Chemical name:17-beta-hydroxy-2-hydroxymethylene-17 alpha-methyl-5 alpha-androstan-3-one Cutting/Bulking:



Bulking Anabolic Rating:320 Active - Life: Less than 16 hours



Drug Class: Highly Androgenic / Anabolic Steroid (Oral)



Average Reported Dosage: Men 50-200 mg daily. Acne: Yes Water Retention: Extreme High Blood Pressure: Yes



Liver Toxic: High



DHT Conversions: DHT-Derived



Decreases HPTA Function: Yes



Aromatization: No



Average Price: Up to $3/tab

TRADE NAMES
ANAPOLON 100 100mg tabs ANAPOLON 50 ANADROL-50 50 MG TABS ANAPOLON 5, 50 MG TABS HEMOGENIN 50 MG TABS SYNASTERON 50 MG TABS OXYMETHOLONE USP XXII 50 MG TABS

Wednesday, February 7, 2007

Anavar (oxandrolone)

Anavar (oxandrolone) Quick overview: Active Life: 8-12 hoursDrug Class: Anabolic/Androgenic Steroid (Oral)Average Dose: Men 20-50 mg/day......Women 5-15 mg/dayAcne: Only in higher dosesWater Retention: RareHigh Blood Pressure: RareLiver Toxic: Yes, c17-alfa-alkylated steroid. Due to low doses, toxicity is low to mediumAromatization: NoneDHT Conversion: LowDecrease HPTA function: Dose depandant Anavar was the old U.S. brand name for the oral steroid oxandrolone, first produced in 1964 by the drug manufacturer Searle. It was designed as an extremely mild anabolic, one that could even be safely used as a growth stimulant in children. One immediately thinks of the standard worry, "steroids will stunt growth". But it is actually the excess estrogen produced by most steroids that is the culprit, just as it is the reason why women stop growing sooner and have a shorter average stature than men. Oxandrolone will not aromatize, and therefore the anabolic effect of the compound can actually promote linear growth. Women usually tolerate this drug well at low doses, and at one time it was prescribed for the treatment of osteoporosis. As the opinions surrounding steroids began to change in the 1980's, prescriptions for oxandrolone began to drop. Lagging sales probably led Searle to discontinue manufacture in 1989, and it had vanished from U.S. pharmacies until recently. Oxandrolone tablets are again available inside the U.S. by BTG, bearing the new brand name Oxandrin. BTG purchased rights to the drug from Searle and it is now manufactured for the new purpose of treating HIV/AIDS related wasting syndrome. Anavar is a mild anabolic with low androgenic activity. Its reduced androgenic activity is due to the fact that it is a derivative of dihydrotestosterone (DHT). Although one might think that this would make it a more androgenic steroid, it in fact creates a steroid that is less androgenic because it is already "5-alpha reduced". In other words, it lacks the capacity to interact with the 5-alpha reductase enzyme and convert to a more potent "dihydro° form. It is a simple matter of where a steroid is capable of being potentiated in the body, and with oxandrolone we do not have the same potential as testosterone, which is several times more active in androgen responsive tissues compared to muscle tissue due to its conversion to DHT. It essence oxandrolone has a balanced level of potency in both muscle and androgenic target tissues such as the scalp, skin and prostate. This is a similar situation as is noted with Primobolan and Winstrol, which are also derived from dihydrotestosterone yet not known to be very androgenic substances. This steroid works well for the promotion of strength and duality muscle mass gains, although it's mild nature makes it less than ideal for bulking purposes. Among bodybuilders it is most commonly used during cutting phases of training when water retention is a concern. The standard dosage for men is in the range of 20-50mg per day, a level that should produce noticeable results. It can be further combined with anabolics like Primobolan and Winstrol to elicit a harder, more defined look without added water retention. Such combinations are very popular and can dramatically enhance the show physique. One can also add strong non-aromatizing androgens like Halotestin, Proviron or trenbolone. In this case the androgen really helps to harden up the muscles, while at the same time making conditions more favorable for fat reduction. Some athletes do choose to incorporate oxandrolone into bulking stacks, but usually with standard bulking drugs like testosterone or Dianabol. The usual goal in this instance is an additional gain of strength, as well as more quality look to the androgen bulk. Women who fear the masculinizing effects of many steroids would be quite comfortable using this drug, as this is very rarely seen with low doses. Here a daily dosage of 5mg should illicit considerable growth without the noticeable androgenic side effects of other drugs. Eager females may wish to addition mild anabolics like Winstrol, Primobolan or Durabolin. When combined with such anabolics, the user should notice faster, more pronounced muscle-building effects, but may also increase the likelihood of androgenic buildup. Studies using low dosages of this compound note minimal interferences with natural testosterone production. Likewise when it is used alone in small amounts there is typically no need for ancillary drugs like Clomid/Nolvadex or HCG. This has a lot to do with the fact that it does not convert to estrogen, which we know has an extremely profound effect on endogenous hormone production. Without estrogen to trigger negative feedback, we seem to note a higher threshold before inhibition is noted. But at higher dosages of course, a suppression of natural testosterone levels will still occur with this drug as with any anabolic/androgenic steroid and therefore require post cycle therapy to restore the HPTA. Anavar is also a 17alpha alkylated oral steroid, carrying an alteration that will put stress on the liver. It is important to point out however that dispite this alteration oxandrolone is generally very well tolerated. While liver enzyme tests will occasionally show elevated values, actual damage due to this steroid is not usually a problem. Bio-Technology General states that oxandrolone is not as extensively metabolized by the liver as other l7aa orals are; evidenced by the fact that nearly a third of the compound is still intact when excreted in the urine. This may have to do with the understood milder nature of this agent (compared to other l7aa orals) in terms of hepatotoxicity. One study comparing the effects of oxandrolone to other agents including as methyltestosterone, norethandrolone, fluoxymesterone and methAndriol clearly supports this notion. Here it was demonstrated that oxandrolone causes the lowest sulfobromophthalein (BSP; a marker of liver stress) retention among all the alkylated orals tested. 20mg of oxandrolone in fact produced 72% less BSP retention than an equal dosage of fluoxyrnesterone, which is a considerable difference being that they possess the same liver-toxic alteration. With such findings, combined with the fact that athletes rarely report trouble with this drug, most feel comfortable believing it to be much safer to use during longer cycles than most of other orals with this distinction. Although this may very well be true, the chance of liver damage still cannot be excluded, especially with hogher dosages. At one time oxandrolone was also looked at as a possible drug for those suffering from disorders of high cholesterol or triglycerides. Early studies showed it to be capable of lowering total cholesterol and triglyceride values in certain types of hyperlipidemic patients, which initially this was thought to signify potential for this drug as a hypo-lipid (lipid lowering) agent. With further investigation we find however that while use of this drug can be linked to a lowering of total cholesterol values, it is such that a redistribution in the ratio of good (HDL) to bad (LDL) cholesterol occurs, usually moving values in an unfavorable direction. This would of course negate any positive effect that the drug might have on triglycerides or total cholesterol, and in fact make it a danger in terms of cardiac risk when taken for prolonged periods of time. Today we understand that as a group anabolic/androgenic steroids produce very unfavorable changes in lipid profiles, and are really not useful in disorders of lipid metabolism. As an oral c17 alpha alkylated steroid, oxandrolone is probably even more risky to use than an injectable esterified injectable such as a testosterone or nandrolone in this regard.

Tuesday, February 6, 2007

Equipoise

Equipoise Buy Equipoise Equipoise (Boldenone Undeclynate), or "EQ" is one of the most widely used compounds by athletes today. Even though it is a vetrinary steroid, the quality of production is quite high due to its use in rather expensive animals. It is one of the safest and most effective steroids used today, by athletes, power lifters and bodybuilders. It can effect slow and continuous muscle mass and strength gains over a prolonged period, and generally cycles with this drug tend to be quite long because of this fact. Gains on a cutting cycle including Eq tend to be high quality lean mass, while bulking cycle gains with Eq aren't as "clean" but still have a very nice quality about them. This could be due to Eq's resistence to being converted to Estrogen, as well as DHT (technically, it converts to Dihydroboldenone). Equipoise has become much more popular in recent years since dosages hit 200mg/ml Men get good results from a 300-600mg weekly total. In the past, this included utilizing an every other day (EOD) injection schedule, because Eq was only available in very low concentrations (50-100mgs/ml). Recently, companies like British Dragon have begun offering Boldenone in a much higher concentration (200mgs/ml) making injections much easier. Women have made excellent progress with dosages of 50-100mg total weekly doses, and this usually means a 1 injections weekly schedule. Women as a rule, seem to prefer less scar-tissue build up than men are comfortable with. In this dose range, women almost never report virilizing side effects, and usually only experienced an elevated libido. Increased hair growth on face and legs is, of course, possible (though not probable).. Liver toxicity is not an issue with Boldenone, and it can be used for long times on either a bulking or cutting cycle, very safely. It has a reputation for appetite and red blood cell production stimulating effects, and this makes it very nice for a bulking cycle. Obviously with increased red blood cell count an increase in oxygen transport was also realized, as was improved nutrient transport, making less food become more efficient...a very nice effect for a cutting cycle. Athletes generally stacked Boldenone with testosterone and Anadrol for mass cycles. Dianabol, due to it's close resemblance to Eq chemically, is not usually used interchangably with Anadrol in cycles containing EQ (a rare exception). Cutting, or pre-contest cycles including Boldenone often include Trenbolones, Winstrol. With the afforementioned drugs, an anti-estrogen is generally not necessary. Reported Characteristics Boldenone Undeclynate 1,4-androstadiene-3-one-17b-ol Cutting/Bulking:Both Anabolic Rating: 100 Active-Life: 7-9 days Drug Class: Anabolic /Androgenic steroid (for injection) Average Reported Dosage: Men 300-600mg weekly Women 50-100mg weekly Acne: Rare Water Retention: Low High Blood Pressure: Rare Aromatization: About 50% of testosterone Liver Toxic: No DHT Conversion: No (*converts to DHB) Decreases HPTA function: Yes Average Price: $150/10ml bottle Trade Names EQUIPOISE 200MG/ML (British Dragon) ULTRAGAN 100 100MG/ML BOLDEBAL-H 50MG/ML EQUIPOISE 25MG,50MG, /ML ULTRAGAN 50 50MG/ML GANABOL 25MG, 50MG/ML PACE 25MG/ML VENBOL 25MG/ML

Sunday, February 4, 2007

Deca Durabolin

Deca Durabolin


Like any field of activity these days, those in the fitness and muscle building industry have their own vocabulary. Two words you will hear from fitness buffs are “stacks” and “cycles.” Stacking and cycling refer to the combination of supplements to obtain optimal muscle mass, quicker recovery and maximum strength.

Sellers of substances like Deca Durabolin also offer cycle programs – running from four weeks to 14 weeks – and using a combination of substances that are supposed to be effective in meeting fitness and muscle growth goals. Gym fanatics who are intent on packing on their muscles will give anything to have that body builder look – even take Deca Durabolin.
The manufacturers of Deca Durabolin have categorically stated that misuse of this substance for body building purposes is strongly discouraged. To use it other than for medical reasons can incur major health risks.

Although the components of Deca Durabolin - nandrolone decanoate – is contained in many generic compounds, most athletes associate these two to Deca Durabolin. It is available in 5.0 mg/ml and 100 mg/ml. The product is the most popular injectable steroid and it helps the muscle store larger amounts of nitrogen, thus gaining a positive nitrogen balance.

Deca Durabolin Use

Another characteristic of Deca Durabolin is that it stores more water in connective tissues, and in doing so appears to cure or diminish pain in the joints such as in the shoulder, knee and elbow. Deca Durabolin is most sought after by athletes right before a competition. But when competitions are accompanied by doping tests, participants must stay away from Deca Durabolin since the metabolites stay in urine for up to eighteen months.

One significant disadvantage of Deca Durabolin is its hefty price. In the US, a 50 mg ampoule costs between $10.00 and $12.00. In higher doses for example – 200 mg – the price can go as high as $30.00 per ampoule. It enjoys a wide following, so consumers are cautioned about the proliferation of fakes.

Writer Bill Roberts says that “the drug is moderately effective at doses of 400 mg/week. The long half-life of nandrolone decanoate makes it unsuited to short alternating cycles, but suitable for more traditional cycles, with a built-in self-tapering effect in the weeks following the last injection.” Another web site, reported that for maximum effect in building muscle mass and strength with anabolic steroids, there are three well-known compounds that work well together, and has not been disputed so far: sustanon, dianabol, and deca durabolin.
When combining each of their own properties, they produce excellent results. First time users can expect a gain of 30 pounds over an eight-week period. Common brands of Deca Durabolin are Norma Hellas, Organon, and Karachi.

Saturday, February 3, 2007

Dianabol

Dianabol is one of the most highly effective mass building steroids ever created. It was, in fact, created specifically for athletes to use to improve performance (although it was claimed to have theraputic ability). It provideds highly impressive weight and strength gains for most users. Experiencing a 2-3kg weight gain per week is not unheard of, especially in novices. It must be noted that alot if this is water weight, and that with higher dosages gynecomastia (bitch tits), high blood pressure, and acne could occur. Dianabol (Methandrostenlone) when taken orally becomes active very rapidly, but only remains active for less than half a day. Often, for this reason, dosages were spread through the day. Ciba, the original makers of Dianabol claimed that 10 mgs of the product was enough for full androgen replacement in a man, and this dose increased androgen anabolic activity roughly 5 times over normal and provided a reduction in natural cortisol activity of between 50-70%. Despite this, many athletes take 50-100mgs daily. It would appear that over 50mgs/day, there is a point of diminishing return. Dianabol is most commonly found in tablet form Since Dianabol (often called D-bol by athletes) is a 17aa compound, side effects such as increased liver values (toxicity) are to be expected, although they generally return to normal quickly after the athlete stops taking the product. In addition, as previously noted, gyno, heavy water retention (and raised blood pressure as a result), and acne were all commonly reported side effects of D-bol use. Interestingly, some users note a sense of well being during use of this drug, which is quite pronounced. This is the exact opposite of Anadrol, which is noted for an "unwell" feeling in users. This product is also available in an injectable form from both British Dragon (in oil) as well as under the Reforvit-B name (which has the addition of B vitamins) which is suspended in water and is quite frankly a very painful injection, and not often used for this reason. TRADE NAMES NAPOSIM 5MG TABS METHANDO (Akrihin) METHANABOL (British Dragon) AVERBOL 25 injectable, 25mg/ml British Dragon ANABOL TABS 5MG TABS ANABOLIN 5MG TABS ANDOREDAN 5MG TABS BIONABOL 2,5MG TABS DIALONE 5MG TABS DIANABOL 5MG ENCEPHAN 5MG TABS METANABOL 1,5MG TABS METHANDROSTENOLONUM 5MG TABS NEROBOL 5MG TABS PRONABOL-5 5MG TABS STENOLON 1,5MG TABS TRENERGIC 5MG CAPS NAPOSIM 5MG TABS D-BOL 10MG CAPSVETERINARY: ANABOLIKUM 2.5% 25MG/ML;50ML METANDIOBOL 25MG/ML;50ML D-BOL INJECTION 25MG/MLReported Characteristics Pharmaceutical Name:Methandrostenolone Chemical Structure:17a-methyl-17b-hydroxy-1,4-androstadien-3-one Cutting/Bulking:Bulking Anabolic Rating:90-210 Active-Life: 6-8 hours (24 for injectable) Drug Class: Anabolic/androgenic steroid Average Reported Dosage: Men 25-50 mg daily Acne: Possible Water Retention: Yes High Blood Pressure: Aromatization: Yes Liver Toxic: Yes DHT conversion: No Decreases HPTA function: Inhibitory Average Price: .50cents-$1 per 5-10mg tab